Trial · NCT07912567
Effect of Midazolam Given at Induction on Recall of Propofol Injection Pain
NCT07912567, Phase 4, Not yet recruiting, Atlas University
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Effect of Midazolam Given at Induction on Recall of Propofol Injection Pain. Trials, record NCT07912567. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07912567
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effect of Midazolam Given at Induction on Recall of Propofol Injection Pain
- NCT number
- NCT07912567
- Status
- Not yet recruiting
- Phases
- Phase 4
- Enrollment
- 150 participants, estimated
- Lead sponsor
- Atlas University
- Conditions
- Propofol Injection Pain, Postoperative Recall of Pain, Preoperative Anxiety
- Interventions
- Midazolam, Lidocaine Hydrochloride 2%, Propofol 1%, Sodium Chloride 0.9%
- First posted
- 2026-11-03
- Last updated
- 2026-11-03
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Postoperative recall of propofol injection pain | Postoperative period on the day of surgery, after recovery from anesthesia 30 minutes after arrival in the post-anesthesia care unit (PACU) | Proportion of participants who report remembering pain at the injection site during propofol injection, assessed by asking each participant once after adequate postoperative recovery. Compared between Group M (midazolam + propofol), Group L (lidocaine-propofol mixture), and Group P (propofol alone). |
| Secondary | Severity of propofol injection pain | At the Baseline, During propofol administration (at the time of injection, ) | Severity of pain during propofol injection graded by the investigator on a 4-point scale (1: no pain; 2: mild arm withdrawal; 3: marked arm withdrawal; 4: verbal expression of pain). Higher scores indicate more pain. Compared between the three groups. |
| Secondary | Relationship between preoperative anxiety and propofol injection pain | During propofol injection and 30 minutes after arrival in the post-anesthesia care unit (PACU) | Preoperative anxiety is measured with a 0-10 Visual Analog Scale (higher scores indicate more anxiety). The relationship between the anxiety score and propofol injection pain score is assessed with Spearman correlation. |
| Other | Sedation level before propofol induction | Before anesthesia induction and 30 minutes after arrival in the post-anesthesia care unit (PACU) | Sedation level assessed with the Ramsay Sedation Scale (1-6; higher scores indicate deeper sedation) and compared between groups. The association between preoperative anxiety levels and the severity of propofol injection pain will be evaluated. Preoperative anxiety will be assessed before anesthesia induction, and propofol injection pain severity will be assessed based on patients' reports 30 minutes after arrival in the post-anesthesia care unit (PACU). |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers4
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Source
- Release
- trials-2026-11-12-0.4.0
- Release manifest SHA-256
- 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
- Registry capture
- 2026-11-12
- Results copy, AACT
- 2026-03-23
- NIH clinical studies file
- 2026-11-13
Source ClinicalTrials.gov
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07912567
GET https://conductscience.org/api/trials/v1/NCT07912567/registered