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Trial · NCT07912931

Registered outcomes28

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
OtherStimulation-Induced Change in Theta/Alpha/Beta PowerAt stimulation activation, and 1 and 3 months after activationLog ratio ln(ON/OFF) computed as for ΔSG; band limits defined in the statistical analysis plan
OtherStimulation-Induced Change in Aperiodic Exponent/OffsetAt stimulation activation, and 1 and 3 months after activationDifference between ON and OFF in the aperiodic exponent/offset of the parameterized LFP power spectrum
OtherInterhemispheric Asymmetry of Anterior Thalamic Spectral PowerFrom stimulation activation to 12 months after activationDifference between left and right hemispheres in device-recorded spectral power over time
OtherChange in Anterior Thalamic Local Field Potential Power Around Patient-Marked Seizures or AurasFrom stimulation activation to 12 months after activationDeviation from the participant's usual narrow-band power around events marked with the patient programmer
OtherProportion of Participants With at Least 50% Reduction in Seizure FrequencyPreoperative baseline and months 7-12 after stimulation activationMonths 7-12 compared with baseline
OtherPercent Reduction in Monthly Seizure Frequency in Months 10-12Preoperative baseline and months 10-12 after stimulation activationSame calculation as the main seizure outcome, using months 10-12
OtherPercent Reduction in Disabling Seizure FrequencyPreoperative baseline and months 7-12 after stimulation activationAll disabling seizures recorded in the diary, regardless of corroboration
OtherLongest Seizure-Free IntervalFrom stimulation activation to 12 months after activationLongest run of days without a diary-recorded seizure

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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