Trial · NCT07913178
Renal Structural and Functional Alterations Following Repeated Ureteroscopic Procedures: An Exploratory Multimodal Imaging Study
NCT07913178, Enrolling by invitation, Region of Southern Denmark
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Renal Structural and Functional Alterations Following Repeated Ureteroscopic Procedures: An Exploratory Multimodal Imaging Study. Trials, record NCT07913178. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07913178
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Renal Structural and Functional Alterations Following Repeated Ureteroscopic Procedures: An Exploratory Multimodal Imaging Study
- NCT number
- NCT07913178
- Status
- Enrolling by invitation
- Enrollment
- 20 participants, estimated
- Lead sponsor
- Region of Southern Denmark
- Conditions
- Urolithiasis, Intrarenal Pressure, MRI Scans, Scintigraphy Quantification, Shear Wave Elastography, Ureteroscopic Lithotripsy
- First posted
- 2026-11-03
- Last updated
- 2026-11-03
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Renal Parenchymal Structural and Functional Assessment by Multiparametric MRI | Baseline (single MRI examination during the study visit). | Renal structure and function are assessed using multiparametric 1.5T MRI, including T1 mapping (GRE TFE), heavily T2-weighted 3D imaging (TSE), diffusion-weighted imaging (DWI; 14 b-values), T2\*-weighted imaging (GRE), and renal arterial flow imaging (GRE). Quantitative measurements include renal parenchymal T1 relaxation times (ms). Regional renal imaging parameters are compared between kidneys within each participant and between patients with repeated unilateral ureteroscopic procedures and healthy controls. |
| Primary | Regional Renal Parenchymal Stiffness Assessed by Ultrasound Elastography | Baseline (single ultrasound examination during the study visit). | Renal parenchymal stiffness is assessed bilaterally using ultrasound elastography, with three repeated measurements obtained in five predefined regions of each kidney. Regional stiffness values are compared between kidneys within each participant and between patients with repeated unilateral ureteroscopic procedures and healthy controls. |
| Primary | Renal Cortical Scarring Assessed by 99mTc-DMSA SPECT | Baseline (single scintigraphic examination during the study visit). | Renal cortical abnormalities consistent with scarring are assessed using 99mTc-DMSA single-photon emission computed tomography (SPECT). The presence and anatomical distribution of cortical defects are evaluated in both kidneys and compared between patients with repeated unilateral ureteroscopic procedures and healthy controls. |
| Secondary | Estimated Glomerular Filtration Rate (eGFR) | Baseline (blood sampling within 30 days before the imaging examination for the healthy controls and on the day of examination for the patients) | Estimated glomerular filtration rate is calculated from serum creatinine to assess global renal function and compare renal function between patients with repeated unilateral ureteroscopic procedures and healthy controls. It alse serves as an eligible criteria for the healthy controls. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers5
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Source
- Release
- trials-2026-11-12-0.4.0
- Release manifest SHA-256
- 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
- Registry capture
- 2026-11-12
- Results copy, AACT
- 2026-03-23
- NIH clinical studies file
- 2026-11-13
Source ClinicalTrials.gov
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07913178
GET https://conductscience.org/api/trials/v1/NCT07913178/registered