Trial · NCT07914075
Kidney Stiffness Measured by Ultrasound in Patients With High Blood Pressure and Healthy Volunteers
NCT07914075, Recruiting, Azienda Ospedaliera di Padova
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Kidney Stiffness Measured by Ultrasound in Patients With High Blood Pressure and Healthy Volunteers. Trials, record NCT07914075. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07914075
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Kidney Stiffness Measured by Ultrasound in Patients With High Blood Pressure and Healthy Volunteers
- NCT number
- NCT07914075
- Status
- Recruiting
- Enrollment
- 240 participants, estimated
- Lead sponsor
- Azienda Ospedaliera di Padova
- Conditions
- Arterial Hypertension, Chronic Kidney Disease, Primary Aldosteronism, Arterial Stenosis
- First posted
- 2026-11-03
- Last updated
- 2026-11-03
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Mean renal cortical stiffness measured by shear wave elastography (SWE), expressed in kilopascals (kPa) | At baseline, single assessment during the renal Doppler ultrasound exam (day 0). | Renal cortical stiffness (Young's modulus) will be measured by real-time SWE during renal artery Doppler ultrasound, using a 4 mm ROI placed in the cortex (≥1 cm below the capsule, avoiding pyramids). Six measurements per kidney (2 per pole: upper, mid, lower) will be acquired, for a total of 12 per patient. The reported value is the arithmetic mean of all 12 measurements per participant. Kidney-level means (6 measurements each) will be used for laterality analyses. This value will be used as the dependent variable in a multivariable linear model to assess its independent association with clinical, anthropometric, biochemical and Doppler covariates. |
| Secondary | Difference in mean renal cortical stiffness (kPa) between hypertensive patients and healthy controls | Baseline (day 0). | Mean of 12 SWE measurements per participant, compared between groups. |
| Secondary | Difference in mean renal cortical stiffness (kPa) between hypertensive patients with and without renal artery stenosis | Baseline (day 0). | Mean SWE value per participant (and kidney-level means for ipsilateral vs. contralateral comparison). Stenosis defined by Doppler ultrasound and/or CT angiography. |
| Secondary | Difference in mean renal cortical stiffness (kPa) between hypertensive patients with and without primary aldosteronism | Baseline (day 0). | Mean of 12 SWE measurements per participant. Primary aldosteronism is biochemically confirmed. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers4
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07914075
GET https://conductscience.org/api/trials/v1/NCT07914075/registered