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Trial · NCT07914400

Registered outcomes18

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryProbing pocket depth (PPD)At baselineProbing pocket depth measured using manual probe at 6 sites around each tooth. Unit: millimeters
PrimaryProbing pocket depth (PPD)90 days after first interventionProbing pocket depth measured using manual probe at 6 sites around each tooth. Unit: millimeters
PrimaryProbing pocket depth (PPD)180 days after first intervention (90 days after second intervention)Probing pocket depth measured using manual probe at 6 sites around each tooth. Unit: millimeters
PrimaryBleeding on probing (BOP)At baselineYes/No after probing pocket depth measurement 6 sites around each tooth. Unit: % (bleeding sites/all sites)
PrimaryBleeding on probing (BOP)90 days after first interventionYes/No after probing pocket depth measurement 6 sites around each tooth. Unit: % (bleeding sites/all sites)
PrimaryBleeding on probing (BOP)180 days after first intervention (90 days after second intervention)Yes/No after probing pocket depth measurement 6 sites around each tooth. Unit: % (bleeding sites/all sites)
PrimaryClinical attachment level (CAL)At baseline
This is the measurement of the position of the soft tissue attachment in relation to the cemento-enamel junction (CEJ). Two measurements are used to calculate the CAL: the probing depth and the distance from the gingival margin to the CEJ. Unit: millimeters
PrimaryClinical attachment level (CAL)90 days after first intervention
This is the measurement of the position of the soft tissue attachment in relation to the cemento-enamel junction (CEJ). Two measurements are used to calculate the CAL: the probing depth and the distance from the gingival margin to the CEJ. Unit: millimeters
PrimaryClinical attachment level (CAL)180 days after first intervention (90 days after second intervention)
This is the measurement of the position of the soft tissue attachment in relation to the cemento-enamel junction (CEJ). Two measurements are used to calculate the CAL: the probing depth and the distance from the gingival margin to the CEJ. Unit: millimeters
PrimaryPlaque index (PI)At baselineYes/No at six sites around each tooth. Unit: % (sites with plaque/all sites)
PrimaryPlaque index (PI)90 days after first interventionYes/No at six sites around each tooth. Unit: % (sites with plaque/all sites)
PrimaryPlaque index (PI)180 days after first intervention (90 days after second intervention)Yes/No at six sites around each tooth. Unit: % (sites with plaque/all sites)
SecondaryChange in serum hs-CRP from pre-instrumentation to 24 hours afterImmediately before and 24 hours after baseline instrumentationThe absolute change in hs-CRP concentration (24-hour post-instrumentation value minus the pre-instrumentation value), expressed in mg/L.
SecondaryChange in serum hs-CRP from pre-instrumentation to 24 hours afterImmediately before and 24 hours after instrumentation at day 90The absolute change in hs-CRP concentration (24-hour post-instrumentation value minus the pre-instrumentation value), expressed in mg/L.
SecondaryDigital gingival surface area (mm²) deviations90 days after first interventionDigital models were superimposed to evaluate gingival surface deviations over time. Changes in gingival surface area were quantified in square millimetres (mm²) and compared between quadrants
SecondaryDigital gingival surface area (mm²) deviations180 days after first interventionDigital models were superimposed to evaluate gingival surface deviations over time. Changes in gingival surface area were quantified in square millimetres (mm²) and compared between quadrants
SecondaryDigital gingival volume (mm³) deviations90 days after first interventionDigital models were superimposed to evaluate gingival surface deviations over time. Changes in gingival volume were quantified in cubic millimetres (mm³) and compared between quadrants
SecondaryDigital gingival volume (mm³) deviations180 days after first interventionDigital models were superimposed to evaluate gingival surface deviations over time. Changes in gingival volume were quantified in cubic millimetres (mm³) and compared between quadrants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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