Methadone Versus Standard of Care for Pain Control in Minimally Invasive Lung Resection Surgery
NCT07914751, Phase 4, Not yet recruiting, Wake Forest University Health Sciences
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Methadone Versus Standard of Care for Pain Control in Minimally Invasive Lung Resection Surgery | ClinicalTrials.gov |
| NCT number | NCT07914751 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Phases | Phase 4 | ClinicalTrials.gov |
| Enrollment | 150 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Wake Forest University Health Sciences | ClinicalTrials.gov |
| Conditions | Pain Management | ClinicalTrials.gov |
| Interventions | Methadone, Standard of Care | ClinicalTrials.gov |
| First posted | 2026-11-04 | ClinicalTrials.gov |
| Last updated | 2026-11-04 | ClinicalTrials.gov |
Registered outcomes 10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Morphine Milligram Equivalents-24 | Postoperative Hour 24 | opioids received for the treatment of postoperative pain and converted to Morphine Milligram Equivalents equivalents between HR 0-24 during hospitalization | ClinicalTrials.gov |
| Primary | Morphine Milligram Equivalents-48 | Postoperative Hour 48 | opioids received for the treatment of postoperative pain and converted to Morphine Milligram Equivalents (MME) between hour 24-48. If subjects have been discharged then only the available data will be used for conversion of MMEs. | ClinicalTrials.gov |
| Primary | Morphine Milligram Equivalents-72 | Postoperative Hour 72 | opioids received for the treatment of postoperative pain and converted to Morphine Milligram Equivalents (MME) between hour 48-72. If subjects have been discharged then only the available data will be used for conversion of MMEs. | ClinicalTrials.gov |
| Primary | Pain Score | Postoperative Hour 24 | Participants will rate their pain level on a scale of 0-10 with 0 being no pain and 10 the worst imaginable pain. | ClinicalTrials.gov |
| Primary | Pain Score | Postoperative Hour 48 | Participants will rate their pain level on a scale of 0-10 with 0 being no pain and 10 the worst imaginable pain. If subjects have been discharged then only the available data will be used. | ClinicalTrials.gov |
| Primary | Pain Score | Postoperative Hour 72 | Participants will rate their pain level on a scale of 0-10 with 0 being no pain and 10 the worst imaginable pain. If subjects have been discharged then only the available data will be used. | ClinicalTrials.gov |
| Secondary | Patient Satisfaction Score | Postoperative hours 24, 48, 72 | Patients will be asked to rate their satisfaction on a scale of 0-10 with 0 being completely dissatisfied and 10 being completely satisfied at hours 24, 48, and 72 (if not discharged ) | ClinicalTrials.gov |
| Secondary | Number of Patients with Respiratory Complications | Postoperative hour 24, 48, 72 | Number of patients with documented respiratory complications- including hypoxia, reintubation, receiving naloxone, hypoventilation, acute renal failure, myocardial infarction, ileus, and mortality. Evaluated at timepoints of occurrence of 0-24, 24-48, and 48-72 (or discharge) | ClinicalTrials.gov |
| Secondary | Pain Scores at Month 3 and Month 6 | Postoperative Month 3 and Month 6 | Participants will rate their pain level on a scale of 0-10 with 0 being no pain and 10 the worst imaginable pain. | ClinicalTrials.gov |
| Secondary | Percentage of subjects with opioid use at Month 3 and Month 6 | 6 months | participants will self report on phone contact the continued use of opioids for the treatment of residual surgical pain at 3 and 6 months postoperatively | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)