Postprandial Hypotension, Frailty and Post-Induction Hypotension in Older Patients Undergoing Noncardiac Surgery
NCT07914920, Recruiting, Konya City Hospital
Trial 8
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Postprandial Hypotension, Frailty and Post-Induction Hypotension in Older Patients Undergoing Noncardiac Surgery | ClinicalTrials.gov |
| NCT number | NCT07914920 | ClinicalTrials.gov |
| Status | Recruiting | ClinicalTrials.gov |
| Enrollment | 200 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Konya City Hospital | ClinicalTrials.gov |
| Conditions | Post-induction Hypotension (PIH), Postprandial Hypotension, Frailty | ClinicalTrials.gov |
| First posted | 2026-11-04 | ClinicalTrials.gov |
| Last updated | 2026-11-10 | ClinicalTrials.gov |
Registered outcomes 22
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Incidence of post-induction hypotension | Up to 20 minutes after induction of anesthesia | Description: Proportion of patients with mean arterial pressure \<65 mmHg and/or a ≥30% decrease from the pre-induction baseline mean arterial pressure (mean of two measurements), measured non-invasively at 2-minute intervals from induction until 20 minutes after induction or surgical incision, whichever occurs first. | ClinicalTrials.gov |
| Secondary | Prevalence of postprandial hypotension | Before and at 30, 60, 90 and 120 minutes after the evening meal on the day before surgery | Proportion of patients with a decrease in systolic blood pressure of ≥20 mmHg from the pre-meal value, or a fall to ≤90 mmHg when the pre-meal value is ≥100 mmHg. | ClinicalTrials.gov |
| Secondary | Change in systolic blood pressure after the meal | Before and at 30, 60, 90 and 120 minutes after the evening meal on the day before surgery | Change in systolic blood pressure (mmHg) from the pre-meal value at 30, 60, 90 and 120 minutes after the meal. | ClinicalTrials.gov |
| Secondary | Change in diastolic blood pressure after the meal | Before and at 30, 60, 90 and 120 minutes after the evening meal on the day before surgery | Change in diastolic blood pressure (mmHg) from the pre-meal value at 30, 60, 90 and 120 minutes after the meal. | ClinicalTrials.gov |
| Secondary | Change in mean arterial pressure after the meal | Before and at 30, 60, 90 and 120 minutes after the evening meal on the day before surgery | Change in mean arterial pressure (mmHg) from the pre-meal value at 30, 60, 90 and 120 minutes after the meal. | ClinicalTrials.gov |
| Secondary | Change in heart rate after the meal | Before and at 30, 60, 90 and 120 minutes after the evening meal on the day before surgery | Change in heart rate (beats/min) from the pre-meal value at 30, 60, 90 and 120 minutes after the meal. | ClinicalTrials.gov |
| Secondary | Maximum postprandial decrease in systolic blood pressure | Before and at 30, 60, 90 and 120 minutes after the evening meal on the day before surgery | Maximum decrease in systolic blood pressure (mmHg) from the pre-meal value. | ClinicalTrials.gov |
| Secondary | Maximum percentage postprandial decrease in systolic blood pressure | Before and at 30, 60, 90 and 120 minutes after the evening meal on the day before surgery. | Maximum decrease in systolic blood pressure from the pre-meal value, expressed as a percentage of the pre-meal value (%). | ClinicalTrials.gov |
| Secondary | Lowest mean arterial pressure after induction | Up to 20 minutes after induction of anesthesia | Lowest mean arterial pressure (mmHg) recorded after induction of anesthesia. | ClinicalTrials.gov |
| Secondary | Maximum decrease in mean arterial pressure after induction | Up to 20 minutes after induction of anesthesia | Maximum decrease in mean arterial pressure (mmHg) from the pre-induction baseline value. | ClinicalTrials.gov |
| Secondary | Maximum percentage decrease in mean arterial pressure after induction | Up to 20 minutes after induction of anesthesia | Maximum decrease in mean arterial pressure from the pre-induction baseline value, expressed as a percentage of the baseline value (%). | ClinicalTrials.gov |
| Secondary | Change in systolic blood pressure after induction | Up to 20 minutes after induction of anesthesia | Change in systolic blood pressure (mmHg) from the pre-induction baseline value. | ClinicalTrials.gov |
| Secondary | Change in diastolic blood pressure after induction | Up to 20 minutes after induction of anesthesia | Change in diastolic blood pressure (mmHg) from the pre-induction baseline value. | ClinicalTrials.gov |
| Secondary | Change in heart rate after induction | Up to 20 minutes after induction of anesthesia | Change in heart rate (beats/min) from the pre-induction baseline value. | ClinicalTrials.gov |
| Secondary | Duration of post-induction hypotension episode | Up to 20 minutes after induction of anesthesia | Time (minutes) from the onset of post-induction hypotension until mean arterial pressure returns to ≥65 mmHg and to \>70% of the pre-induction baseline value. | ClinicalTrials.gov |
| Secondary | Vasopressor/inotrope use after induction | Up to 20 minutes after induction of anesthesia | Proportion of patients receiving at least one dose of a vasopressor or inotropic agent. | ClinicalTrials.gov |
| Secondary | Need for additional vasopressor/inotrope treatment after induction | Up to 20 minutes after induction of anesthesia | Proportion of patients requiring a second bolus or an additional vasopressor or inotropic agent. | ClinicalTrials.gov |
| Secondary | Cumulative ephedrine dose after induction | Up to 20 minutes after induction of anesthesia | Cumulative dose of ephedrine (mg) administered after induction of anesthesia. | ClinicalTrials.gov |
| Secondary | Cumulative norepinephrine dose after induction | Up to 20 minutes after induction of anesthesia | Cumulative dose of norepinephrine (µg), including bolus and infusion doses, administered after induction of anesthesia. | ClinicalTrials.gov |
| Other | Postoperative intensive care unit admission | Day of surgery | Proportion of patients admitted to the intensive care unit after surgery | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 4
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)