Comparison of Sequential vs. Simultaneous Adrenal Vein Sampling
NCT07918794, Completed, Yahao Zhang
Trial 8
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Comparison of Sequential vs. Simultaneous Adrenal Vein Sampling | ClinicalTrials.gov |
| NCT number | NCT07918794 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Enrollment | 238 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Yahao Zhang | ClinicalTrials.gov |
| Conditions | Primary Aldosteronism, Hypertension | ClinicalTrials.gov |
| First posted | 2026-11-05 | ClinicalTrials.gov |
| Last updated | 2026-11-05 | ClinicalTrials.gov |
Registered outcomes 8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Cannulation Success Rate | At the time of the adrenal vein sampling procedure (data collected retrospectively for participants enrolled between September 2022 and December 2024) | The success rate of selective catheterization of the adrenal veins, confirmed by a selectivity index (adrenal vein cortisol / inferior vena cava cortisol) of ≥2. Assessed separately for the left adrenal vein, right adrenal vein, and bilaterally. | ClinicalTrials.gov |
| Secondary | Lateralization Pattern | At the time of the adrenal vein sampling procedure (data collected retrospectively for participants enrolled between September 2022 and December 2024) | The pattern of aldosterone hypersecretion as determined by the lateralization index (LI). LI is calculated as the ratio of the higher to the lower aldosterone-to-cortisol ratio between the two adrenal veins. Lateralization is defined as LI ≥2. Patterns are categorized as no lateralization, left lateralization, or right lateralization. | ClinicalTrials.gov |
| Other | Aldosterone Concentration | At the time of the adrenal vein sampling procedure (data collected retrospectively for participants enrolled between September 2022 and December 2024) | Plasma aldosterone concentration measured in ng/dL from the left adrenal vein, right adrenal vein, and inferior vena cava. Concentrations will be reported separately for each sampling site. | ClinicalTrials.gov |
| Other | Cortisol Concentration | At the time of the adrenal vein sampling procedure (data collected retrospectively for participants enrolled between September 2022 and December 2024) | Plasma cortisol concentration measured in nmol/L from the left adrenal vein, right adrenal vein, and inferior vena cava. Concentrations will be reported separately for each sampling site. | ClinicalTrials.gov |
| Other | Normalized Aldosterone Ratio | At the time of the adrenal vein sampling procedure (data collected retrospectively for participants enrolled between September 2022 and December 2024) | The aldosterone-to-cortisol ratio for each adrenal vein, calculated using aldosterone and cortisol concentrations converted to consistent units. The ratio is unitless and will be reported separately for the left and right adrenal veins. | ClinicalTrials.gov |
| Other | Fluoroscopy Time | At the time of the adrenal vein sampling procedure (data collected retrospectively for participants enrolled between September 2022 and December 2024) | The total duration of fluoroscopy guidance used during the adrenal vein sampling procedure, measured in minutes. | ClinicalTrials.gov |
| Other | Radiation Dose | At the time of the adrenal vein sampling procedure (data collected retrospectively for participants enrolled between September 2022 and December 2024) | The total radiation dose administered to the patient during the adrenal vein sampling procedure, measured in milligray (mGy). | ClinicalTrials.gov |
| Other | Procedure-related Complications | From the start of the adrenal vein sampling procedure up to 24 hours post-procedure (data collected retrospectively for participants enrolled between September 2022 and December 2024) | The incidence of procedure-related adverse events, including but not limited to adrenal vein hematoma, vascular spasm, and catheter entanglement. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)