L-PRF Block vs Composite Graft for Horizontal Ridge Augmentation
NCT07918950, Not applicable, Active not recruiting, Gulf Medical University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | L-PRF Block vs Composite Graft for Horizontal Ridge Augmentation | ClinicalTrials.gov |
| NCT number | NCT07918950 | ClinicalTrials.gov |
| Status | Active not recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 70 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Gulf Medical University | ClinicalTrials.gov |
| Conditions | Alveolar Ridge Resorption After Extraction, Alveolar Bone Loss, Jaw, Edentulous, Partially, Horizontal Ridge Defect | ClinicalTrials.gov |
| Interventions | L-PRF Block with DBBM, Autogenous Bone / DBBM Composite Graft | ClinicalTrials.gov |
| First posted | 2026-11-05 | ClinicalTrials.gov |
| Last updated | 2026-11-05 | ClinicalTrials.gov |
Registered outcomes 9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Horizontal Bone Gain | Baseline ($T_0$) and 6 months post-augmentation surgery ($T_2$ | Linear horizontal ridge width gain (measured in mm) evaluated via 3D superimposition of CBCT DICOM datasets at reference levels 1 mm, 3 mm, and 5 mm apical to the alveolar crest | ClinicalTrials.gov |
| Secondary | Graft Dimensional Stability and Volumetric Reduction | Immediately after augmentation ($T_1$) and 6 months post-augmentation ($T_2$) | Percentage of linear maintenance (%) and dimensional loss (%) of the augmented ridge measured by 3D CBCT DICOM superimpositions comparing immediate post-augmentation to 6 months post-augmentation. | ClinicalTrials.gov |
| Secondary | Buccal Bone Plate Thickness | 6 months post-final prosthetic restoration | adiographic thickness of the facial bone plate (measured in mm) evaluated on CBCT scans around dental implants at the implant shoulder level (Sh0), 2 mm apical (Sh2), and 4 mm apical (Sh4). | ClinicalTrials.gov |
| Secondary | Implant Primary Stability | At implant placement surgery ($T_2$, 6 months post-ridge augmentation) | Assessment of primary stability measured via resonance frequency analysis (RFA) expressed as Implant Stability Quotient (ISQ, scale 1-100) using the Osstell device in mesiodistal and buccolingual directions at implant placement. | ClinicalTrials.gov |
| Secondary | Implant Secondary Stability | At abutment connection surgery ($T_3$, approximately 3 months post-implant placement) | Assessment of secondary stability measured via resonance frequency analysis (RFA) expressed as Implant Stability Quotient (ISQ, scale 1-100) using the Osstell device at second-stage uncovery surgery. | ClinicalTrials.gov |
| Secondary | Histomorphometric Bone Outcomes | 6 months post-ridge augmentation ($T_2$) | Quantitative histomorphometric analysis of trephine bone core biopsies (2 mm diameter $\\times$ 6 mm depth) measuring percentages of newly formed bone (%), residual graft material (%), and connective tissue/marrow spaces (%) | ClinicalTrials.gov |
| Secondary | Postoperative Pain Intensity | Postoperative Days 3 and 7 following augmentation surgery | Patient-reported surgical site pain evaluated using a 10-cm Visual Analog Scale (VAS 0-10, where 0 = no pain and 10 = worst imaginable pain). | ClinicalTrials.gov |
| Secondary | Postoperative Complication Rate | Up to 12 months post-surgery | Incidence of surgical or healing complications, including primary wound dehiscence, graft exposure, infection, hematoma, or donor/recipient site morbidity. | ClinicalTrials.gov |
| Secondary | Patient Satisfaction with Esthetic and Functional Outcomes | 6 months post-final prosthetic restoration ($T_4$) | Patient satisfaction evaluated on a Visual Analog Scale (VAS 0-10) assessing white esthetics (crown appearance), pink esthetics (soft tissue contour), and masticatory function. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)