Serum Estradiol and Endometrial Thickness After Bariatric Surgery in Postmenopausal Women With Obesity
NCT07919054, Not yet recruiting, Kasr El Aini Hospital
Trial 9
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Serum Estradiol and Endometrial Thickness After Bariatric Surgery in Postmenopausal Women With Obesity | ClinicalTrials.gov |
| NCT number | NCT07919054 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Enrollment | 78 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Kasr El Aini Hospital | ClinicalTrials.gov |
| Conditions | Obesity, Morbid, Postmenopause, Endometrial Thickening | ClinicalTrials.gov |
| Interventions | Bariatric surgery, Conventional non-surgical obesity management | ClinicalTrials.gov |
| First posted | 2026-11-05 | ClinicalTrials.gov |
| Last updated | 2026-11-05 | ClinicalTrials.gov |
Registered outcomes 6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change in serum estradiol level from baseline to 12 months, compared between the surgical and non-surgical groups | Baseline and 12 months | Serum estradiol (pg/mL) measured in a venous blood sample drawn under standardized conditions at baseline (before surgery in the surgical group, before starting non-surgical management in the comparison group) and at 12 months. The absolute change (12 months minus baseline) is compared between the bariatric surgery group and the non-surgical group. | ClinicalTrials.gov |
| Primary | Change in endometrial thickness from baseline to 12 months, compared between the surgical and non-surgical groups | Baseline and 12 months | Endometrial thickness (mm) measured by transvaginal ultrasound in the sagittal plane at the point of maximum thickness, using the same standardized technique at each visit. The absolute change (12 months minus baseline) is compared between the bariatric surgery group and the non-surgical group. | ClinicalTrials.gov |
| Primary | Correlation between the change in serum estradiol level and the change in endometrial thickness | Baseline to 12 months | Correlation coefficient (Pearson or Spearman, as appropriate) between the 12-month change in serum estradiol (pg/mL) and the 12-month change in transvaginal endometrial thickness (mm) across both study groups. | ClinicalTrials.gov |
| Secondary | Percentage of excess weight loss (%EWL) | 6 and 12 months | Weight lost since baseline divided by baseline excess weight, multiplied by 100, recorded at 6 and 12 months in both groups. | ClinicalTrials.gov |
| Secondary | Correlation between change in BMI and serum estradiol level | 6 and 12 months | Correlation coefficient (Pearson or Spearman, as appropriate) between the change in BMI (kg/m²) from baseline and serum estradiol (pg/mL) at 6 and 12 months, across both groups. | ClinicalTrials.gov |
| Secondary | Correlation between change in BMI and endometrial thickness | 6 and 12 months | Correlation coefficient (Pearson or Spearman, as appropriate) between the change in BMI (kg/m²) from baseline and transvaginal endometrial thickness (mm) at 6 and 12 months, across both groups. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)