Integrated Medicine for Sepsis: An RCT With Phenotyping
NCT07920692, Not applicable, Not yet recruiting, Henan University of Traditional Chinese Medicine
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Integrated Medicine for Sepsis: An RCT With Phenotyping | ClinicalTrials.gov |
| NCT number | NCT07920692 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 320 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Henan University of Traditional Chinese Medicine | ClinicalTrials.gov |
| Conditions | Sepsis | ClinicalTrials.gov |
| Interventions | Syndrome-Differentiated Chinese Herbal Medicine, Matching Placebo for Syndrome-Differentiated Chinese Herbal Medicine | ClinicalTrials.gov |
| First posted | 2026-11-06 | ClinicalTrials.gov |
| Last updated | 2026-11-06 | ClinicalTrials.gov |
Registered outcomes 8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | 28-Day All-Cause Mortality | Day 28 after enrollment | The proportion of participants who die from any cause within 28 days after enrollment. | ClinicalTrials.gov |
| Primary | Sequential Organ Failure Assessment (SOFA) Score | Baseline (Day 0), Day 7, Day 14, and Day 28 after enrollment | The Sequential Organ Failure Assessment (SOFA) score will be used to assess dysfunction in six organ systems: respiratory, coagulation, hepatic, cardiovascular, central nervous system, and renal function. The total score ranges from 0 to 24, with higher scores indicating more severe organ dysfunction. | ClinicalTrials.gov |
| Secondary | Acute Physiology and Chronic Health Evaluation II (APACHE II) Score | Baseline (Day 0), Day 7, Day 14, and Day 28 after enrollment | Disease severity will be assessed using the Acute Physiology and Chronic Health Evaluation II (APACHE II) score. The total score ranges from 0 to 71, with higher scores indicating greater disease severity. | ClinicalTrials.gov |
| Secondary | Length of ICU Stay | From ICU admission through hospital discharge or Day 28, whichever occurs first | The duration of ICU stay will be calculated in days from ICU admission to the first discharge from the ICU. For participants who are readmitted to the ICU, ICU readmission and the cumulative duration of ICU stay will also be recorded. | ClinicalTrials.gov |
| Secondary | Ventilator-Free Days Within 28 Days | From enrollment through Day 28 | The number of days during the first 28 days after enrollment that a participant is alive and free from invasive mechanical ventilation will be calculated. | ClinicalTrials.gov |
| Secondary | ICU-Free Days Within 28 Days | From enrollment through Day 28 | The number of days through Day 28 during which a participant is alive and remains outside the ICU after the first ICU discharge will be calculated. | ClinicalTrials.gov |
| Secondary | Time to Sustained Resolution of Fever | From enrollment through Day 28 | The time from enrollment to normalization of body temperature sustained for more than 72 hours will be recorded. A transient reduction in body temperature following administration of antipyretic medication will not be considered sustained resolution of fever. | ClinicalTrials.gov |
| Secondary | Duration of Antimicrobial Therapy | From enrollment through hospital discharge or Day 28, whichever occurs first. | The cumulative duration of intravenous and/or oral antimicrobial therapy during hospitalization will be recorded in days. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)