The Role of Multidimensional Prognostic Index (MPI) in the Assessment of Elderly Patients underGoING Cardiac REHABilitation
NCT07921758, Completed, Istituti Clinici Scientifici Maugeri SpA
Trial 8
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | The Role of Multidimensional Prognostic Index (MPI) in the Assessment of Elderly Patients underGoING Cardiac REHABilitation | ClinicalTrials.gov |
| NCT number | NCT07921758 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Enrollment | 202 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Istituti Clinici Scientifici Maugeri SpA | ClinicalTrials.gov |
| Conditions | Heart Failure, Acute Coronary Syndromes (ACS), Cardiac Surgery | ClinicalTrials.gov |
| First posted | 2026-11-06 | ClinicalTrials.gov |
| Last updated | 2026-11-06 | ClinicalTrials.gov |
Registered outcomes 2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Proportion of patients classified as being at high risk according to Multidimensional Prognostic Index (MPI) | Baseline (day 1), discharge (up to five days), and 3 months (Day 90) | The primary endpoint is the prevalence of frailty, defined as an MPI score between 0.67 and 1.00, assessed at: Baseline (admission to the cardiac rehabilitation unit); Hospital discharge; Three months after discharge. Patients with an MPI score ranging from 0.67 to 1.00 will be classified as frail. Frailty prevalence at each time point will be calculated as the proportion of patients with an MPI score between 0.67 and 1.00 divided by the total number of evaluated patients, and will be expressed as a percentage: Frailty prevalence (%) = (Number of patients with MPI 0.67-1.00 / Total number of assessed patients) × 100. | ClinicalTrials.gov |
| Secondary | Prognostic value of the Multidimensional Prognostic Index (MPI) score at discharge for 1-year all-cause mortality. | 1 year | The association between discharge MPI score and one-year event-free survival (free from all-cause mortality and hospital readmission) will be investigated using Cox proportional hazards regression analysis. Hazard ratios and 95% confidence intervals will be calculated to quantify the increase in the risk of death or hospitalization associated with each 0.1-point increment in MPI score. Higher MPI values are expected to reflect a greater degree of frailty and a correspondingly higher risk of adverse clinical outcomes. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
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Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
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Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
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Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
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Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
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Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
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Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
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Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)