Bioactive Glass With or Without a Collagen Membrane for Periodontal Intrabony Defects
NCT07922577, Not applicable, Completed, Medical University of Bialystok
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Bioactive Glass With or Without a Collagen Membrane for Periodontal Intrabony Defects | ClinicalTrials.gov |
| NCT number | NCT07922577 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 40 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Medical University of Bialystok | ClinicalTrials.gov |
| Conditions | Periodontitis | ClinicalTrials.gov |
| Interventions | Periodontal regenerative surgery with bioactive glass alone, Periodontal regenerative surgery with bioactive glass and a collagen membrane | ClinicalTrials.gov |
| First posted | 2026-11-06 | ClinicalTrials.gov |
| Last updated | 2026-11-06 | ClinicalTrials.gov |
Registered outcomes 6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change in Clinical Attachment Level | Baseline (before surgery), 6 months and 12 years after surgery. | Clinical attachment level (CAL) was measured in millimeters as the distance from the cementoenamel junction to the bottom of the periodontal pocket at the treated intrabony defect site using a PCP-UNC15 periodontal probe. Measurements were performed by a calibrated examiner blinded to treatment allocation. Changes were calculated relative to baseline. A decrease in CAL indicates clinical attachment gain. | ClinicalTrials.gov |
| Secondary | Change in Probing Depth | Baseline (before surgery), 6 months and 12 years after surgery. | Probing depth (PD) was measured in millimeters from the gingival margin to the bottom of the periodontal pocket using a PCP-UNC15 periodontal probe. The greatest probing depth within the pocket corresponding to the treated intrabony defect was recorded. Changes were assessed relative to baseline. A decrease indicates improvement. | ClinicalTrials.gov |
| Secondary | Change in Gingival Recession | Baseline (before surgery), 6 months and 12 years after surgery. | Gingival recession (GR) was measured in millimeters from the cementoenamel junction to the gingival margin using a PCP-UNC15 periodontal probe. Positive values indicated a gingival margin located apical to the cementoenamel junction. Changes at the treated site were assessed relative to baseline. An increase indicates greater recession. | ClinicalTrials.gov |
| Secondary | Change in Full-Mouth Plaque Score | Baseline (before surgery), 6 months and 12 years after surgery. | Full-mouth plaque score (FMPS) was calculated as the percentage of examined sites with detectable plaque, assessed at six sites around each tooth present. Scores range from 0% to 100%, with higher values indicating more plaque. Changes were assessed relative to baseline. | ClinicalTrials.gov |
| Secondary | Change in Radiographic Intrabony Defect Height | Baseline (before surgery), 6 months and 12 years after surgery. | Radiographic intrabony defect height (Rx-OH) was measured in millimeters on standardized intraoral periapical radiographs. Changes were assessed relative to baseline. A decrease indicates a reduction in the radiographic vertical dimension of the defect. | ClinicalTrials.gov |
| Secondary | Change in Radiographic Intrabony Defect Width | Baseline (before surgery), 6 months and 12 years after surgery. | Radiographic intrabony defect width (Rx-OW) was measured in millimeters on standardized intraoral periapical radiographs. Changes were assessed relative to baseline. A decrease indicates a reduction in the radiographic horizontal dimension of the defect. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)