Negative Pressure Wound Therapy Versus Direct Skin Closure for Burst Abdomen
NCT07922629, Not applicable, Completed, Alexandria University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Negative Pressure Wound Therapy Versus Direct Skin Closure for Burst Abdomen | ClinicalTrials.gov |
| NCT number | NCT07922629 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 45 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Alexandria University | ClinicalTrials.gov |
| Conditions | Burst Abdomen, Surgical Wound Dehiscence, Abdominal Wound Dehiscence | ClinicalTrials.gov |
| Interventions | Negative Pressure Wound Therapy, Direct Skin Closure | ClinicalTrials.gov |
| First posted | 2026-11-06 | ClinicalTrials.gov |
| Last updated | 2026-11-06 | ClinicalTrials.gov |
Registered outcomes 12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Definitive Aponeurotic (Fascial) Closure | Up to 3 months after the index procedure | Proportion of participants in whom complete closure of the abdominal wall fascia (aponeurosis) was achieved, assessed clinically. | ClinicalTrials.gov |
| Secondary | Intra-Abdominal Pressure | At the first, second and third postoperative measurement sessions (within the first week after the index procedure) | Intra-abdominal pressure in mmHg, measured indirectly as urinary bladder pressure through a Foley catheter connected to a saline-filled monitoring system. | ClinicalTrials.gov |
| Secondary | Number of Sessions to Definitive Closure | up to 3 months | Number of dressing or operative sessions required until definitive fascial closure. | ClinicalTrials.gov |
| Secondary | Time to Definitive Closure | Up to 3 months | Time in days from the index procedure to definitive fascial closure | ClinicalTrials.gov |
| Secondary | Length of Hospital Stay | From the index procedure until discharge, up to 3 month | Number of days from the index procedure to hospital discharge | ClinicalTrials.gov |
| Secondary | Surgical Site Infection | Up to 3 months | Proportion of participants with surgical site infection, diagnosed clinically. | ClinicalTrials.gov |
| Secondary | Enteroatmospheric or Enterocutaneous Fistul | Up to 3 months | Proportion of participants who develop an enteroatmospheric or enterocutaneous fistula. | ClinicalTrials.gov |
| Secondary | Unplanned Reoperation | Up to 3 months | Proportion of participants requiring an unplanned return to the operating room for a complication. | ClinicalTrials.gov |
| Secondary | Abdominal Compartment Syndrome | From the index procedure until discharge, up to 3 months | Proportion of participants who develop abdominal compartment syndrome, defined as sustained intra-abdominal pressure above 20 mmHg with new organ dysfunction. | ClinicalTrials.gov |
| Secondary | Intraoperative Complications | During the index procedure | Proportion of participants with intraoperative complications such as bleeding or visceral injury during the index procedure. | ClinicalTrials.gov |
| Secondary | Readmission | Up to 3 months | Proportion of participants readmitted to hospital after discharge. | ClinicalTrials.gov |
| Secondary | All-Cause Mortality | Up to 3 months | Proportion of participants who die from any cause. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)