Cardiopulmonary Complications of Electronic Cigarettes
NCT07924007, Not applicable, Not yet recruiting, University of Alberta
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Cardiopulmonary Complications of Electronic Cigarettes | ClinicalTrials.gov |
| NCT number | NCT07924007 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 480 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | University of Alberta | ClinicalTrials.gov |
| Conditions | Electronic Cigarette Use, Cannabis Use | ClinicalTrials.gov |
| Interventions | Lower body positive and negative pressure, Exercise | ClinicalTrials.gov |
| First posted | 2026-11-09 | ClinicalTrials.gov |
| Last updated | 2026-11-09 | ClinicalTrials.gov |
Registered outcomes 9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Diffusing capacity of carbon monoxide (DLCO) | Time Frame: Days 2 and 3. Measurements will be taken during each stage of intervention, after a minimum of 2 minutes from the onset of each stage. | Diffusing capacity of carbon monoxide (DLCO) in selected exercise intensities, lower-body pressures, and body positions. DLCO is measured using the single-breath dual gas pulmonary diffusing capacity for nitric oxide and carbon monoxide technique. | ClinicalTrials.gov |
| Primary | Capillary blood volume (Vc) | Time Frame: Days 2 and 3. Measurements will be taken during each stage of intervention, after a minimum of 2 minutes from the onset of each stage. | Capillary blood volume is a component of DLCO and is measured with the single-breath dual gas pulmonary diffusing capacity for nitric oxide and carbon monoxide technique. | ClinicalTrials.gov |
| Primary | Membrane diffusing capacity (Dm) | Time Frame: Days 2 and 3. Measurements will be taken during each stage of intervention, after a minimum of 2 minutes from the onset of each stage. | Membrane diffusing capacity is a component of DLCO and is measured with the single-breath dual gas pulmonary diffusing capacity for nitric oxide and carbon monoxide technique. | ClinicalTrials.gov |
| Secondary | Exercise capacity | Average peak VO2 recorded during the final 30seconds of the highest workload. | Exercise capacity (VO2peak) will be measured using an incremental exercise test. | ClinicalTrials.gov |
| Secondary | Physical activity - Step Count | Measured for 7 days after visit 1 | Physical activity (number of steps per day) will be measured using an activity monitor. | ClinicalTrials.gov |
| Secondary | Physical activity - Moderate to Vigorous | Measured for 7 days after visit 1 | Number of minutes spent doing moderate to vigorous physical activity will be measured using an activity monitor. | ClinicalTrials.gov |
| Secondary | Cardiac structure and function | Time Frame: Day 4. Measurements will be taken during each stage of intervention, after a minimum of 2 minutes from the onset of each stage. | Right ventricular systolic pressure during each intervention. | ClinicalTrials.gov |
| Secondary | Blood volume | Time Frame: Visit 5. Measurement will be taken through study completion, an average of 10 minutes after the intervention. | Total blood volume estimated using the carbon monoxide rebreathe method. | ClinicalTrials.gov |
| Secondary | Pulmonary vascular volumes | Time Frame: Visit 6. Measurement will be taken through study completion, an average of 30 minutes per scan. | Chest computed tomorgraphy (CT) scan | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 5
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)