Balance Training and Resting Brain Activity in Knee Osteoarthritis: A Randomized Controlled Trial
NCT07924748, Not applicable, Completed, Qingdao Municipal Hospital
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Balance Training and Resting Brain Activity in Knee Osteoarthritis: A Randomized Controlled Trial | ClinicalTrials.gov |
| NCT number | NCT07924748 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 74 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Qingdao Municipal Hospital | ClinicalTrials.gov |
| Conditions | Osteoarthritis, Knee | ClinicalTrials.gov |
| Interventions | Conventional Rehabilitation (Muscle-Strengthening Training), Standardized Balance Training | ClinicalTrials.gov |
| First posted | 2026-11-09 | ClinicalTrials.gov |
| Last updated | 2026-11-09 | ClinicalTrials.gov |
Registered outcomes 7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Timed Up and Go Test(TUG) | Baseline and after 8 weeks of intervention | The time in seconds required to rise from an armchair (about 45 cm high), walk 3 meters at a normal pace, turn around, walk back, and sit down. A shorter time indicates better functional mobility and dynamic balance. | ClinicalTrials.gov |
| Secondary | Berg Balance Scale (BBS) | Baseline and after 8 weeks of intervention | A 14-item standardized measure of static and dynamic balance; each item is scored 0-4, with a total score of 0-56. Higher scores indicate better balance. | ClinicalTrials.gov |
| Secondary | Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) | Baseline and after 8 weeks of intervention | A 24-item questionnaire covering pain, stiffness, and physical function. Higher scores indicate worse symptoms and greater functional limitation. | ClinicalTrials.gov |
| Secondary | Visual Analogue Scale (VAS) | Baseline and after 8 weeks of intervention | A 0-10 scale for knee pain intensity, where 0 means no pain and 10 means the worst imaginable pain. | ClinicalTrials.gov |
| Secondary | Computerized Static Posturography | Baseline and after 8 weeks of intervention | Objective balance measures from a force plate, including plantar pressure distribution (load percentage across foot regions) and center-of-gravity sway angular velocity (deg/sec) during single-leg stance with eyes open and closed. Lower sway velocity indicates better postural stability. | ClinicalTrials.gov |
| Secondary | Resting-State Functional Magnetic Resonance Imaging (rs-fMRI) | Baseline and after 8 weeks of intervention | Brain imaging measures of spontaneous neural activity and functional connectivity, including amplitude of low-frequency fluctuation (ALFF), regional homogeneity (ReHo), and functional connectivity (FC), used to assess balance-related brain function. | ClinicalTrials.gov |
| Other | Incidence of Adverse Events | Throughout the 8-week intervention period | Any study-related adverse events, including muscle soreness, fatigue, falls, and MRI-related anxiety or discomfort, with severity and causal relationship documented. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|---|---|
| 16371799 | BACKGROUND | PubMed |
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)