Autonomic and Immune Effects of Regional Anesthesia in Total Hip Arthroplasty
NCT07925658, Not applicable, Not yet recruiting, Poznan University of Medical Sciences
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Autonomic and Immune Effects of Regional Anesthesia in Total Hip Arthroplasty | ClinicalTrials.gov |
| NCT number | NCT07925658 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 165 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Poznan University of Medical Sciences | ClinicalTrials.gov |
| Conditions | Hip Ostearthritis | ClinicalTrials.gov |
| Interventions | PENG Block, LIA | ClinicalTrials.gov |
| First posted | 2026-11-09 | ClinicalTrials.gov |
| Last updated | 2026-11-09 | ClinicalTrials.gov |
Registered outcomes 25
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change in Systemic Immune-Inflammation Index (SII) | 24 hours after surgery | Comparison of the change in Systemic Immune-Inflammation Index from baseline to postoperative 24 hours among the three study groups. | ClinicalTrials.gov |
| Secondary | Neutrophil-to-Lymphocyte Ratio (NLR) | 24 hours after surgery | Comparison of the change in neutrophil-to-lymphocyte ratio among the three study groups. | ClinicalTrials.gov |
| Secondary | Neutrophil-to-Lymphocyte Ratio (NLR) | 12 hours after surgery | Comparison of the change in neutrophil-to-lymphocyte ratio among the three study groups. | ClinicalTrials.gov |
| Secondary | Neutrophil-to-Lymphocyte Ratio (NLR) | 48 hours after surgery | Comparison of the change in neutrophil-to-lymphocyte ratio among the three study groups. | ClinicalTrials.gov |
| Secondary | Platelet-to-Lymphocyte Ratio (PLR) | 24 hours after surgery | Comparison of the change in platelet-to-lymphocyte ratio among the three study groups. | ClinicalTrials.gov |
| Secondary | Platelet-to-Lymphocyte Ratio (PLR) | 48 hours after surgery | Comparison of the change in platelet-to-lymphocyte ratio among the three study groups. | ClinicalTrials.gov |
| Secondary | Platelet-to-Lymphocyte Ratio (PLR) | 12 hours after surgery | Comparison of the change in platelet-to-lymphocyte ratio among the three study groups. | ClinicalTrials.gov |
| Secondary | Postoperative pain intensity | 2 hours after surgery | Comparison of postoperative pain intensity assessed using the Numeric Rating Scale (NRS; 0-10) at rest. | ClinicalTrials.gov |
| Secondary | Postoperative pain intensity at movement | 2 hours after surgery | Comparison of postoperative pain intensity assessed using the Numeric Rating Scale (NRS; 0-10) at movement. | ClinicalTrials.gov |
| Secondary | Postoperative pain intensity at movement | 6 hours after surgery | Comparison of postoperative pain intensity assessed using the Numeric Rating Scale (NRS; 0-10) at movement. | ClinicalTrials.gov |
| Secondary | Postoperative pain intensity at movement | 12 hours after surgery | Comparison of postoperative pain intensity assessed using the Numeric Rating Scale (NRS; 0-10) at movement. | ClinicalTrials.gov |
| Secondary | Postoperative pain intensity at movement | 24 hours after surgery | Comparison of postoperative pain intensity assessed using the Numeric Rating Scale (NRS; 0-10) at movement. | ClinicalTrials.gov |
| Secondary | Postoperative pain intensity at movement | 48 hours after surgery | Comparison of postoperative pain intensity assessed using the Numeric Rating Scale (NRS; 0-10) at movement. | ClinicalTrials.gov |
| Secondary | Postoperative pain intensity | 6 hours after surgery | Comparison of postoperative pain intensity assessed using the Numeric Rating Scale (NRS; 0-10) at rest. | ClinicalTrials.gov |
| Secondary | Postoperative pain intensity | 12 hours after surgery | Comparison of postoperative pain intensity assessed using the Numeric Rating Scale (NRS; 0-10) at rest. | ClinicalTrials.gov |
| Secondary | Postoperative pain intensity | 24 hours after surgery | Comparison of postoperative pain intensity assessed using the Numeric Rating Scale (NRS; 0-10) at rest. | ClinicalTrials.gov |
| Secondary | Postoperative pain intensity | 48 hours after surgery | Comparison of postoperative pain intensity assessed using the Numeric Rating Scale (NRS; 0-10) at rest. | ClinicalTrials.gov |
| Secondary | Postoperative opioid consumption | 48 hours after surgery | Comparison of cumulative opioid consumption during the postoperative period, expressed as intravenous morphine milligram equivalents (MME). | ClinicalTrials.gov |
| Secondary | Time to first rescue analgesia | 48 hours after surgery | Comparison of the time from the end of surgery to the first administration of rescue opioid analgesia. | ClinicalTrials.gov |
| Secondary | Systemic Immune-Inflammation Index (SII) | 24 hours after surgery | Comparison of the change in the Systemic Immune-Inflammation Index (SII) among the three study groups. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)