TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patients With Severe Aortic Stenosis
NCT07926022, Recruiting, Alexandria University
Trial 9
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patients With Severe Aortic Stenosis | ClinicalTrials.gov |
| NCT number | NCT07926022 | ClinicalTrials.gov |
| Status | Recruiting | ClinicalTrials.gov |
| Enrollment | 100 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Alexandria University | ClinicalTrials.gov |
| Conditions | Aortic Stenosis Disease, Coronary Artery Disease (CAD) | ClinicalTrials.gov |
| Interventions | TAVI, PCI, SAVR, CABG | ClinicalTrials.gov |
| First posted | 2026-11-09 | ClinicalTrials.gov |
| Last updated | 2026-11-09 | ClinicalTrials.gov |
Registered outcomes 7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | In-Hospital Composite Endpoint | Periprocedurally | he occurrence of at least one of the following events periprocedurally from the index procedure through hospital discharge, reported as the number and percentage of participants experiencing one or more events: All-cause in-hospital mortality. Non-fatal myocardial infarction. Non-fatal stroke or transient ischemic attack (TIA). Emergency coronary or valve reintervention. High-degree atrioventricular (AV) block. Major bleeding (Bleeding Academic Research Consortium \[BARC\] type ≥3). Each participant will be counted only once in the composite endpoint, regardless of the number of events experienced. | ClinicalTrials.gov |
| Primary | One-Year Composite Endpoint | within 12 months after the procedure | he occurrence of at least one of the following events within 12 months after the index procedure: All-cause mortality. Non-fatal myocardial infarction. Non-fatal stroke or transient ischemic attack (TIA). High-degree atrioventricular (AV) block. Major bleeding (Bleeding Academic Research Consortium \[BARC\] type ≥3). The composite endpoint will be reported as the number and percentage of participants experiencing at least one of the listed events. Each participant will be counted only once, regardless of the number of events experienced. | ClinicalTrials.gov |
| Secondary | All-cause mortality | Within 12 months after the index procedure. | Measure: All-cause mortality Description: Number and percentage of participants who died from any cause. Unit: Participants | ClinicalTrials.gov |
| Secondary | Non-fatal myocardial infarction | Within 12 months after the index procedure. | Measure: Non-fatal myocardial infarction. Description: Number and percentage of participants experiencing non-fatal myocardial infarction. Unit: Participants | ClinicalTrials.gov |
| Secondary | Non-fatal stroke or TIA | Within 12 months after the index procedure. | Measure: Non-fatal stroke or transient ischemic attack (TIA) Description: Number and percentage of participants experiencing non-fatal stroke or TIA. Unit: Participants | ClinicalTrials.gov |
| Secondary | High-degree heart block | Within 12 months after the index procedure. | Measure: High-degree atrioventricular (AV) block Description: Number and percentage of participants developing high-degree AV block. Unit: Participants | ClinicalTrials.gov |
| Secondary | Major bleeding | Within 12 months after the index procedure. | Measure: Major bleeding (BARC type ≥3) Description: Number and percentage of participants experiencing major bleeding classified as BARC type 3 or higher. Unit: Participants | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)