Posterior Versus Transmuscular Quadratus Lumborum Block in Children Undergoing Lower Abdominal Surgery
NCT07926269, Not applicable, Not yet recruiting, Beni-Suef University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Posterior Versus Transmuscular Quadratus Lumborum Block in Children Undergoing Lower Abdominal Surgery | ClinicalTrials.gov |
| NCT number | NCT07926269 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 70 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Beni-Suef University | ClinicalTrials.gov |
| Conditions | Postoperative Pain, Inguinal Hernias, Undescended Testis, Hydrocele | ClinicalTrials.gov |
| Interventions | Posterior Quadratus Lumborum Block (QL2), Transmuscular Quadratus Lumborum Block (QL3) | ClinicalTrials.gov |
| First posted | 2026-11-09 | ClinicalTrials.gov |
| Last updated | 2026-11-09 | ClinicalTrials.gov |
Registered outcomes 11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Total Cumulative Opioid Consumption in the First 24 Hours | First 24 hours postoperatively | Total cumulative dose of intraoperative and postoperative rescue opioids administered during the first 24 hours postoperatively, converted to intravenous morphine-equivalent doses (mg/kg) using standard conversion ratios and normalized to body weight. A lower numerical value indicates a superior clinical outcome (greater opioid-sparing effect and reduced opioid requirement). | ClinicalTrials.gov |
| Secondary | Postoperative Pain Intensity Scores | At 0 (PACU arrival), 1, 2, 4, 6, 12, 18, and 24 hours postoperatively | Postoperative pain intensity measured using the Face, Legs, Activity, Cry, Consolability (FLACC) behavioral pain scale. Scores range from 0 to 10, where 0 represents no pain (relaxed and comfortable; best outcome) and 10 represents severe pain/discomfort (worst outcome). Lower numerical scores represent better pain control. | ClinicalTrials.gov |
| Secondary | Time to First Rescue Analgesia Request | Up to 24 hours postoperatively | Time elapsed (in minutes) from arrival in the Post-Anesthesia Care Unit (PACU) until the first administration of rescue analgesic (triggered by a FLACC score ≥4). A higher numerical value (longer duration of time) indicates a superior clinical outcome (prolonged block duration and delayed pain onset). | ClinicalTrials.gov |
| Secondary | Block Execution Time | Intraoperatively (during block performance) | Total time required to perform the ultrasound-guided regional block, measured in seconds from initial placement of the ultrasound transducer on the skin to needle withdrawal. Lower execution times represent greater technical ease and efficiency (better procedural performance). | ClinicalTrials.gov |
| Secondary | Number of Needle Passes and Redirections | Intraoperatively (during block performance) | Number of discrete needle skin punctures and forward redirections required to achieve correct needle tip positioning within the intended target fascial plane. A lower count indicates easier needle placement and less tissue trauma (better procedural outcome). | ClinicalTrials.gov |
| Secondary | Incidence and Severity of Postoperative Nausea and Vomiting | At 0, 1, 2, 4, 6, 12, 18, and 24 hours postoperatively | Presence and severity of postoperative nausea and vomiting assessed using a 4-point scale (0 = no nausea or vomiting \[best outcome\], 1 = mild nausea, 2 = moderate nausea or single emetic episode, 3 = severe nausea or multiple emetic episodes requiring antiemetic rescue \[worst outcome\]). Lower scores represent a better clinical outcome. | ClinicalTrials.gov |
| Secondary | Postoperative Sedation Score | At 0, 1, 2, 4, 6, 12, 18, and 24 hours postoperatively | Sedation level evaluated using the University of Michigan Sedation Scale (UMSS), ranging from 0 (awake and alert; normal state) to 4 (unarousable to noxious stimuli; severe sedation/respiratory risk). Lower scores (specifically 0 to 1) represent desirable postoperative alertness and faster recovery. | ClinicalTrials.gov |
| Secondary | Incidence and Degree of Lower Limb Motor Blockade | At 1, 4, and 8 hours postoperatively | Motor weakness evaluated using a modified Bromage scale (0 = full flexion of knees and feet / no motor block \[best safety outcome\], 1 = partial flexion, 2 = movement of feet only, 3 = complete paralysis of lower limb \[worst outcome\]). A score of 0 indicates an optimal motor-sparing sensory block without unwanted lumbar plexus involvement. | ClinicalTrials.gov |
| Secondary | Parental Satisfaction Score | 24 hours postoperatively | Parental or legal guardian overall satisfaction with post-surgical pain management evaluated on a 5-point Likert scale (1 = very dissatisfied \[worst outcome\], 2 = dissatisfied, 3 = neutral, 4 = satisfied, 5 = very satisfied \[best outcome\]). Higher numerical scores represent a superior clinical outcome. | ClinicalTrials.gov |
| Secondary | Time to Post-Anesthesia Discharge Readiness | Up to 24 hours postoperatively | Time elapsed (in minutes) from PACU arrival until the child satisfies all criteria of the modified pediatric Post-Anesthesia Discharge Scoring System (PADSS). A lower numerical value (shorter duration of time in minutes) indicates a better outcome (faster recovery and earlier discharge readiness). | ClinicalTrials.gov |
| Secondary | Incidence of Block-Related Adverse Events and Complications | Through 24 hours postoperatively | Total count and percentage of procedural complications (including vascular puncture, LAST, peritoneal injury, localized hematoma, or infection). A lower number (ideally 0) indicates a superior safety profile. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)