Cardiac Cycle Efficiency and Vasoactive-Inotropic Support After Cardiac Surgery
NCT07926360, Recruiting, Bursa City Hospital
Trial 8
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Cardiac Cycle Efficiency and Vasoactive-Inotropic Support After Cardiac Surgery | ClinicalTrials.gov |
| NCT number | NCT07926360 | ClinicalTrials.gov |
| Status | Recruiting | ClinicalTrials.gov |
| Enrollment | 68 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Bursa City Hospital | ClinicalTrials.gov |
| Conditions | Cardiac Surgical Procedures, Low Cardiac Output Syndrome | ClinicalTrials.gov |
| First posted | 2026-11-09 | ClinicalTrials.gov |
| Last updated | 2026-11-10 | ClinicalTrials.gov |
Registered outcomes 6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Predictive Performance of CCE for High Vasoactive-Inotropic Support | First 24 hours after ICU admission | Area under the ROC curve of Cardiac Cycle Efficiency measured 30 minutes after separation from cardiopulmonary bypass for predicting maximum Vasoactive-Inotropic Score (VISmax) ≥15. VISmax is the highest hourly VIS during the first 24 hours after ICU admission. | ClinicalTrials.gov |
| Secondary | Predictive Performance of Early CCE (T3 and Mean T3-T4) | First 24 hours after ICU admission | ROC analysis of CCE at 15 minutes after bypass and mean of 15- and 30-minute CCE values for predicting VISmax ≥15. | ClinicalTrials.gov |
| Secondary | Vasoactive-Inotropic Score | At intensive care unit admission and 6 and 24 hours after admission. | The Vasoactive-Inotropic Score (VIS) will be assessed at intensive care unit admission and at 6 and 24 hours after admission. VIS will be calculated as dopamine + dobutamine + (100 × epinephrine) + (100 × norepinephrine) + (50 × levosimendan) + (10,000 × vasopressin). Drug doses are expressed in µg/kg/min, except vasopressin, which is expressed in units/kg/min. The minimum score is 0, and there is no fixed maximum score. Higher scores indicate worse outcomes, reflecting greater vasoactive and inotropic support requirements; lower scores indicate better outcomes, reflecting lower support requirements. | ClinicalTrials.gov |
| Secondary | Serum Lactate and Lactate Clearance | 24 hours | Lactate (mmol/L) at ICU admission, 6 and 24 hours; lactate clearance in the first 6 hours (%). | ClinicalTrials.gov |
| Secondary | In-Hospital Mortality | Until hospital discharge, up to 30 days | All-cause death during hospital stay. | ClinicalTrials.gov |
| Secondary | Duration of Mechanical Ventilation | Until hospital discharge, up to 30 days | Time from ICU admission to extubation (hours) and need for reintubation. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)