Spatiotemporal Modeling of Tuberculosis Transmission Risk in a Clinical Waiting Room Using Environmental and Patient Movement Data: Impact of Simple Patient Management Interventions
NCT07927881, Completed, Centre for Infectious Disease Research in Zambia
Trial 8
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Spatiotemporal Modeling of Tuberculosis Transmission Risk in a Clinical Waiting Room Using Environmental and Patient Movement Data: Impact of Simple Patient Management Interventions | ClinicalTrials.gov |
| NCT number | NCT07927881 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Enrollment | 1,000 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Centre for Infectious Disease Research in Zambia | ClinicalTrials.gov |
| Conditions | Tuberculosis (TB) | ClinicalTrials.gov |
| First posted | 2026-11-10 | ClinicalTrials.gov |
| Last updated | 2026-11-10 | ClinicalTrials.gov |
Registered outcomes 3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Patient flow, clustering, occupancy, CO₂, particles, bioaerosols and clinical/epidemiological characteristics. | 6 MONTHS | Estimated TB transmission risk will be calculated using a spatiotemporal model incorporating environmental conditions and patient movement/occupancy data. The outcome will be summarized as the change in modeled transmission-risk estimates between the pre-intervention and intervention periods. | ClinicalTrials.gov |
| Primary | TB TRANSMISSION | 6 MONTHS | We aim to establish a novel approach for estimating the risk of TB transmission in a healthcare clinic in a high TB/HIV setting in Zambia using data on patient characteristics, indoor CO₂ and bioaerosol measurements, and patient flows from video sensors. We will use these data to parameterise a novel mathematical model of TB transmission in primary care clinics, identify the drivers of transmission risk, and estimate the impact of interventions targeting patient flows on the risk of TB transmission. | ClinicalTrials.gov |
| Secondary | TB TRANSMISSION | 6 months | To determine patient flow, patient clustering, and the number of patients at a given time point using anonymous video sensors and environmental data (CO₂ levels, particle concentrations, bioaersol), as well as to study clinical features and to study epidemiological and clinical characteristics of patients seen at the outpatient department, such as TB/HIV suspicion, using clinical information from medical records. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)