Unplanned Hospitalization and Emergency Department Use in Patients With Head and Neck Cancer Receiving Radiotherapy
NCT07929194, Not yet recruiting, Xiangya Hospital of Central South University
Trial 8
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Unplanned Hospitalization and Emergency Department Use in Patients With Head and Neck Cancer Receiving Radiotherapy | ClinicalTrials.gov |
| NCT number | NCT07929194 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Enrollment | 657 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Xiangya Hospital of Central South University | ClinicalTrials.gov |
| Conditions | Head and Neck Neoplasms | ClinicalTrials.gov |
| First posted | 2026-11-10 | ClinicalTrials.gov |
| Last updated | 2026-11-10 | ClinicalTrials.gov |
Registered outcomes 8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Incidence of Unplanned Hospitalization | From Day 1 of radiotherapy fraction through 30 days after radiotherapy completion (approximately 3 months) | Proportion of participants with at least one unplanned inpatient admission, defined as any unscheduled inpatient admission encompassing (i) outpatient-to-inpatient transfer during radiotherapy, (ii) emergency department-led admission, and (iii) readmission after treatment discharge; planned elective admissions are excluded. | ClinicalTrials.gov |
| Secondary | Incidence of Emergency Department (ED) Visits | From Day 1 of radiotherapy fraction through 30 days after radiotherapy completion (approximately 3 months) | Proportion of participants with at least one unscheduled ED visit (with or without admission), and total number of ED visits per participant. | ClinicalTrials.gov |
| Secondary | Reasons for Unplanned Hospitalization and ED Visits | From Day 1 of radiotherapy fraction through 30 days after radiotherapy completion (approximately 3 months) | Distribution of primary reasons categorized by clinical review (e.g., mucositis/oral pain, dehydration or inadequate oral intake, infection/fever, dysphagia, bleeding, nausea/vomiting). | ClinicalTrials.gov |
| Secondary | Incidence of Severe (Grade ≥3) Radiation-Induced Oral Mucositis | From Day 1 of radiotherapy fraction through 30 days after radiotherapy completion (approximately 3 months) | Proportion of participants developing grade ≥3 oral mucositis measured by the tool of CTCAE v5.0 | ClinicalTrials.gov |
| Secondary | Incidence of Severe (Grade ≥3) radiation dermatitis | From Day 1 of radiotherapy fraction through 30 days after radiotherapy completion (approximately 3 months) | Proportion of participants with grade ≥3 radiation dermatitis measured by CTCAE v5.0 | ClinicalTrials.gov |
| Secondary | Longitudinal Changes in average score of Patient-Reported Symptom Burden (MDASI-HN) | Baseline (the first radiotherapy fraction) , 15th radiotherapy fraction, and the final day of radiotherapy | measured by MDASI-HN symptom-severity and interference scores (0-10 scales) | ClinicalTrials.gov |
| Secondary | Incidence of Radiotherapy Interruption | From Day 1 of radiotherapy fraction through 30 days after radiotherapy completion (approximately 3 months) | Proportion of participants with any unplanned radiotherapy interruption (≥1 fraction missed) | ClinicalTrials.gov |
| Secondary | Incidence of Significant Weight Loss | From Day 1 of radiotherapy fraction through 30 days after radiotherapy completion (approximately 3 months) | Proportion of participants with weight loss ≥10% in the completion of radiotherapy compared with baseline | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 5
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)