Retro-SCTL Space Block vs Rhomboid Intercostal Block for Analgesia After Modified Radical Mastectomy
NCT07929441, Not applicable, Not yet recruiting, Mansoura University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Retro-SCTL Space Block vs Rhomboid Intercostal Block for Analgesia After Modified Radical Mastectomy | ClinicalTrials.gov |
| NCT number | NCT07929441 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 88 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Mansoura University | ClinicalTrials.gov |
| Conditions | Breast Cancer, Modified Radical Mastectomy, Postoperative Pain | ClinicalTrials.gov |
| Interventions | Retro Superior Costotransverse Ligament Space Block, Rhomboid Intercostal Block | ClinicalTrials.gov |
| First posted | 2026-11-10 | ClinicalTrials.gov |
| Last updated | 2026-11-10 | ClinicalTrials.gov |
Registered outcomes 14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Cumulative 24-hour intravenous morphine consumption | From arrival in the post-anesthesia care unit (PACU) to 24 hours postoperatively | Total rescue IV morphine (mg) given in the first 24 hours after surgery. Rescue morphine 2 mg IV is given when NRS at rest is ≥ 4 or on patient request, repeated every 10 minutes until NRS is \< 4. | ClinicalTrials.gov |
| Secondary | Postoperative pain scores at rest and on movement | 1, 2, 4, 6, 12 and 24 hours after PACU arrival | Pain intensity on the Numerical Rating Scale (0 = no pain, 10 = worst imaginable pain), at rest and during ipsilateral shoulder abduction to 90°. If abduction isn't tolerated, three deep breaths are used instead. | ClinicalTrials.gov |
| Secondary | Time to first rescue analgesia | From PACU arrival to the first rescue morphine dose, assessed up to 24 hours postoperatively | Time (minutes) from PACU arrival to the first rescue morphine dose. Patients who need no rescue are censored at 24 hours. | ClinicalTrials.gov |
| Secondary | Total intraoperative fentanyl consumption | During surgery: from induction of anesthesia to end of surgery (approximately 2-3 hours) | Total fentanyl (mcg) given during surgery, including the induction dose and rescue doses (0.5 mcg/kg). Rescue is triggered when MAP or HR rises \> 20% above the pre-incision baseline for ≥ 2 minutes. | ClinicalTrials.gov |
| Secondary | Extent of sensory block | 30 minutes after block injection | Number of dermatomes (T1-T6 and axilla) with reduced or absent cold sensation (ethyl chloride) on the operative side compared with the contralateral side. Block success is defined as ≥ 3 contiguous dermatomes. | ClinicalTrials.gov |
| Secondary | Incidence of postoperative nausea and vomiting (PONV) | Assessed at 1, 2, 4, 6, 12, and 24 hours after PACU arrival (cumulative incidence up to 24 hours) | Number of patients with any episode of nausea, retching or vomiting. | ClinicalTrials.gov |
| Secondary | Rescue antiemetic requirement | Assessed at 1, 2, 4, 6, 12, and 24 hours after PACU arrival (cumulative requirement up to 24 hours) | Number of patients needing rescue metoclopramide 10 mg IV. | ClinicalTrials.gov |
| Secondary | Block performance time | Periprocedural: during block performance, before induction of anesthesia | Time (seconds) from first placement of the ultrasound probe on the skin to needle withdrawal. | ClinicalTrials.gov |
| Secondary | Number of needle passes | Periprocedural: during block performance, before induction of anesthesia | Number of needle redirections needed to reach the target plane (maximum 3). | ClinicalTrials.gov |
| Secondary | Incidence of block-related adverse events | From block performance up to 24 hours postoperatively | Number of patients with any of the following: hypotension (MAP \< 65 mmHg or \> 20% decrease from baseline) bradycardia (HR \< 50 bpm) vascular puncture, hematoma or puncture-site infection pneumothorax (confirmed by lung ultrasound or chest X-ray) contralateral sensory block suggesting epidural spread local anesthetic systemic toxicity | ClinicalTrials.gov |
| Secondary | Sedation score | 1, 2, 4, 6, 12 and 24 hours after PACU arrival | Ramsay Sedation Scale (1 = anxious/agitated to 6 = no response). | ClinicalTrials.gov |
| Secondary | Quality of recovery (QoR-15) | Baseline (preoperatively, on the day of surgery) and 24 hours postoperatively | Quality of Recovery-15 questionnaire score (range 0-150; higher scores mean better recovery). | ClinicalTrials.gov |
| Secondary | Patient satisfaction with postoperative analgesia | 24 hours postoperatively | 5-point Likert scale (1 = very dissatisfied, 5 = very satisfied). | ClinicalTrials.gov |
| Secondary | Persistent postsurgical pain | 3 months postoperatively | Incidence of pain at or near the surgical site present on ≥ 4 of the 7 days before assessment, by structured telephone interview. Intensity is rated on the NRS (0-10), and neuropathic features are screened with the DN4 interview questionnaire (DN4i, score 0-7; ≥ 3 suggests neuropathic pain). | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)