Corrective Spinal Surgery for Severe Spinal Curvature in People With Ankylosing Spondylitis
NCT07930611, Not applicable, Not yet recruiting, China-Japan Friendship Hospital
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Corrective Spinal Surgery for Severe Spinal Curvature in People With Ankylosing Spondylitis | ClinicalTrials.gov |
| NCT number | NCT07930611 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 35 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | China-Japan Friendship Hospital | ClinicalTrials.gov |
| Conditions | Ankylosing Spondylitis | ClinicalTrials.gov |
| Interventions | pedicle subtraction osteotomy | ClinicalTrials.gov |
| First posted | 2026-11-12 | ClinicalTrials.gov |
| Last updated | 2026-11-12 | ClinicalTrials.gov |
Registered outcomes 33
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change in Bath Ankylosing Spondylitis Functional Index(BASFI) from baseline to 12 months after surgery (ΔBASFI) | at baseline, 6 months, and 12 months | on the 0-10 scale. A negative change indicates improved function. | ClinicalTrials.gov |
| Primary | Change in T1 pelvic angle (TPA) from baseline to 12 months after surgery (ΔTPA) | at baseline, 6 months, and 12 months | TPA will be measured on the standing lateral full-spine radiograph as the angle between the line connecting the center of the T1 vertebral body to the bicoxofemoral axis and the line connecting the bicoxofemoral axis to the midpoint of the superior endplate of S1. TPA incorporates both global spinal inclination and pelvic retroversion and provides a global measure of sagittal alignment. A negative change indicates improved function. | ClinicalTrials.gov |
| Secondary | the seventh cervical vertebra (C7)-sagittal vertical axis(SVA) | at baseline, 6 months, and 12 months | Measured on a full-length standing lateral radiograph as the horizontal distance from the C7 plumb line to the posterior-superior corner of the S1 endplate. Unit: millimeters (mm) | ClinicalTrials.gov |
| Secondary | spinosacral angle(SSA) | at baseline, 6 months, and 12 months | Measured as the angle between the C7 plumb line and the sacral endplate line. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | Sagittal Pelvic Angle(SPA) | at baseline, 6 months, and 12 months | Measured as the angle between the sacral endplate line and the line connecting the femoral head axis to the C7 plumb line. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | pelvic incidence(PI) | at baseline, 6 months, and 12 months | Measured as the angle between the line perpendicular to the sacral endplate at its midpoint and the line from that midpoint to the femoral head axis. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | pelvic tilt(PT) | at baseline, 6 months, and 12 months | Measured as the angle between the vertical line and the line from the femoral head axis to the sacral endplate midpoint. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | sacral slope(SS) | at baseline, 6 months, and 12 months | Measured as the angle between the sacral endplate line and the horizontal line. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | Pelvic Incidence(PI)-lumbar lordosis(LL) mismatch | at baseline, 6 months, and 12 months | Calculated as PI minus LL. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | global kyphosis(GK) | at baseline, 6 months, and 12 months | Measured as the angle between the superior endplate of the upper-most tilted vertebra and the inferior endplate of the lower-most tilted vertebra in the kyphotic segment. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | thoracic kyphosis(TK) | at baseline, 6 months, and 12 months | Measured as the Cobb angle between the superior endplate of T4 and the inferior endplate of T12. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | oracolumbar kyphosis(TLK) | at baseline, 6 months, and 12 months | Measured as the Cobb angle between the superior endplate of T10 and the inferior endplate of L2. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | lumbar lordosis(LL) | at baseline, 6 months, and 12 months | Measured as the Cobb angle between the superior endplate of L1 and the superior endplate of S1. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | Kyphosis apex vertebra | at baseline, 6 months, and 12 months | Identified as the vertebra at the apex of the maximal kyphotic curve on the lateral radiograph. Unit: vertebral level (e.g.T8, T9) | ClinicalTrials.gov |
| Secondary | Local osteotomy angle | at baseline, 6 months, and 12 months | Measured as the angle created at the osteotomy site between the superior and inferior endplates of the resected/adjacent vertebrae on intraoperative or postoperative imaging. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | the second cervical vertebra(C2)-the seventh cervical vertebra(C7) lordosis. | at baseline, 6 months, and 12 months | Measured as the Cobb angle between the inferior endplate of C2 and the inferior endplate of C7. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | the second cervical vertebra(C2)-the seventh cervical vertebra(C7) sagittal vertical axis(SVA) | at baseline, 6 months, and 12 months | Measured as the horizontal distance from the C2 plumb line (vertical line from the C2 centroid) to the posterior-superior corner of C7. Unit: millimeters (mm) | ClinicalTrials.gov |
| Secondary | the first thoracic vertebra(T1) slope | at baseline, 6 months, and 12 months | Measured as the angle between the superior endplate of T1 and the horizontal line. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | the first thoracic vertebra(T1) angle | at baseline, 6 months, and 12 months | T1 angle measured between the T1 endplate line and the line from the T1 centroid to the C7 centroid. Unit: degrees (°) | ClinicalTrials.gov |
| Secondary | Neck tilt | at baseline, 6 months, and 12 months | Neck tilt measured as the angle between the vertical line and the line from the sternal notch to the T1 centroid | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.3.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 4a570df2e7274cee2d4fa2959402fab41880e2cd412e4b590390035fbea69391 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
Release trials-2026-11-12-0.3.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.