Evaluation of Thenar Muscle Biomechanics and Thermal Sensory Thresholds in Carpal Tunnel Syndrome
NCT07931092, Completed, Karamanoğlu Mehmetbey University
Trial 8
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Evaluation of Thenar Muscle Biomechanics and Thermal Sensory Thresholds in Carpal Tunnel Syndrome | ClinicalTrials.gov |
| NCT number | NCT07931092 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Enrollment | 43 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Karamanoğlu Mehmetbey University | ClinicalTrials.gov |
| Conditions | Carpal Tunnel Syndrome (CTS), Quantitative Sensory Testing (QST), MyotonPRO | ClinicalTrials.gov |
| First posted | 2026-11-12 | ClinicalTrials.gov |
| Last updated | 2026-11-12 | ClinicalTrials.gov |
Registered outcomes 3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Myotonometry | during the procedure | The viscoelastic and mechanical properties of the abductor pollicis brevis (APB) muscle, the primary superficial abductor of the thenar muscle group, were evaluated using a digital myotonometer (MyotonPRO, Myoton AS, Tallinn, Estonia). Participants were seated in a resting position with the forearm supported in full supination to ensure complete muscular relaxation. The probe was positioned perpendicular (90°) to the skin over the most prominent point of the APB muscle belly. Following standard mechanical preloading (0.18 N), the device delivered three consecutive mechanical impulses of 0.4 N with a duration of 15 ms at 0.8-second intervals. | ClinicalTrials.gov |
| Primary | Quantitative sensory analysis | during the procedure | Quantitative sensory testing of small fibers (Aδ and C) was conducted using a Medoc TSA-2 Air analyzer (Medoc Advanced Medical Systems, Ramat Yishay, Israel) with a 30 × 30 mm Peltier thermode placed over the median nerve-innervated thenar eminence. From a baseline of 32 °C (safety limits: 0-50 °C) and a ramp rate of 1 °C/s, participants pressed a response button upon perceiving sensation to determine cold detection (CDT; Aδ fibers), warm detection (WDT; C fibers), cold pain (CPT), and heat pain (HPT) thresholds. Each parameter was recorded across three consecutive trials, and the mean values (°C) were used for analysis. | ClinicalTrials.gov |
| Secondary | Hand grip/finger pinch strength | during the procedure | Quantitative assessment of hand and finger motor performance strictly adhered to American Society of Hand Therapists guidelines. With participants seated upright (shoulder adducted and neutrally rotated, elbow flexed, forearm supported in mid-rotation, and wrist slightly dorsiflexed), maximal handgrip strength was measured using a Baseline hydraulic hand dynamometer (90-kg capacity; Fabrication Enterprises, White Plains, NY, USA), and two-point pinch strength between the thumb and index finger was evaluated with a Baseline hydraulic pinch gauge. To prevent muscle fatigue and central effort loss, 60-second rest intervals were provided between consecutive trials, and the mean of three valid maximum isometric attempts was recorded as peak force in kilograms. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
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Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 4
The papers the trial lists on ClinicalTrials.gov.
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.3.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 4a570df2e7274cee2d4fa2959402fab41880e2cd412e4b590390035fbea69391 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
Release trials-2026-11-12-0.3.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.