Effectiveness of Two Diaphragmatic Strengthening Programs on Symptoms of LPR as Measured by the Reflux Symptom Index (RSI) and the Reflux Disease Questionnaire (RDQ)
NCT07931105, Not applicable, Completed, Mayo Clinic
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Effectiveness of Two Diaphragmatic Strengthening Programs on Symptoms of LPR as Measured by the Reflux Symptom Index (RSI) and the Reflux Disease Questionnaire (RDQ) | ClinicalTrials.gov |
| NCT number | NCT07931105 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 69 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Mayo Clinic | ClinicalTrials.gov |
| Conditions | Laryngeal/Pharyngeal Reflux (LPR) | ClinicalTrials.gov |
| Interventions | Standard abdominal breathing, Resisted Exercise | ClinicalTrials.gov |
| First posted | 2026-11-12 | ClinicalTrials.gov |
| Last updated | 2026-11-12 | ClinicalTrials.gov |
Registered outcomes 2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change in Reflux Symptom Index (RSI) Score | Baseline, 1 month, 3 months, 6 months | The RSI is a 9-item questionnaire evaluating the severity of nine common LPR-related throat and voice symptoms over the past month. Each symptom is rated from 0 (no problem) to 5 (severe problem), with total scores ranging from 0-45. Higher scores indicate greater laryngopharyngeal reflux symptom severity. | ClinicalTrials.gov |
| Primary | Change in Reflux Disease Questionnaire (RDQ) Score | Baseline, 1 month, 3 months, 6 months | The RDQ is used to quantify gastroesophageal reflux disease (GERD) symptoms in adults. The RDQ has six symptom items (heartburn, regurgitation, dyspepsia). Each item is rated on two separate 0-5 scales: Frequency (0 = never, 5 = daily) and Severity (0 = did not have, 5 = severe). Each item's frequency + severity sum is averaged across the two items in that symptom dimension, and the overall RDQ score is the mean of all 12 ratings (6 items × 2 facets). Higher scores indicate greater reflux symptom severity. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
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Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
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Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
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Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
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Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
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Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
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Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
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Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.3.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 4a570df2e7274cee2d4fa2959402fab41880e2cd412e4b590390035fbea69391 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
Release trials-2026-11-12-0.3.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.