Does the Form Matter? Effects of Standard and Enteric-coated Sodium Bicarbonate Capsules on Repeated Maximal Cycling Performance, Acid-base Balance, and Gastrointestinal Issues in Men in a Randomized Placebo-controlled Crossover Trial
NCT07933237, Not applicable, Completed, The Jerzy Kukuczka Academy of Physical Education in Katowice
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Does the Form Matter? Effects of Standard and Enteric-coated Sodium Bicarbonate Capsules on Repeated Maximal Cycling Performance, Acid-base Balance, and Gastrointestinal Issues in Men in a Randomized Placebo-controlled Crossover Trial | ClinicalTrials.gov |
| NCT number | NCT07933237 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 19 participants, actual | ClinicalTrials.gov |
| Lead sponsor | The Jerzy Kukuczka Academy of Physical Education in Katowice | ClinicalTrials.gov |
| Conditions | Sodium Bicarbonate, Gastrointestinal Symptoms, Healthy Adult Males | ClinicalTrials.gov |
| Interventions | SB-N, SB-EC, Double Wingate test, PLA | ClinicalTrials.gov |
| First posted | 2026-11-12 | ClinicalTrials.gov |
| Last updated | 2026-11-12 | ClinicalTrials.gov |
Registered outcomes 8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Mean Power (W) | At each intervention visit (three visits completed within 2 weeks of the first intervention visit) | Mean power output (W) was measured during a 30-second Wingate anaerobic test performed at each intervention visit under one of three supplementation conditions. Mean power output was compared between supplementation conditions. | ClinicalTrials.gov |
| Primary | HCO3- [mmol/L] | Baseline, 30, 60, 90, and 120 minutes after supplement ingestion, 5 minutes after the first Wingate test, 5, 10, and 15 minutes after the second Wingate test | ClinicalTrials.gov | |
| Secondary | Peak Power (W) | During each intervention visit, within 2 weeks of the first intervention visit | Peak power output (W) was recorded during each 30-second Wingate anaerobic test and compared between the three supplementation conditions. | ClinicalTrials.gov |
| Secondary | Fatigue Slope (W·s-¹) | During each intervention visit, within 2 weeks of the first intervention visit | Fatigue slope (W/s) was calculated from the decline in power output during each 30-second Wingate anaerobic test and compared between the three supplementation conditions. | ClinicalTrials.gov |
| Secondary | Rate of Fatigue (%) | During each intervention visit, within 2 weeks of the first intervention visit | Rate of fatigue (%) was calculated from the reduction in power output during each 30-second Wingate anaerobic test and compared between the three supplementation conditions. | ClinicalTrials.gov |
| Secondary | Lactate (mmol·L-¹) | Baseline, 30, 60, 90, and 120 minutes after supplement ingestion, 5 minutes after the first Wingate test, 5, 10, and 15 minutes after the second Wingate test | ClinicalTrials.gov | |
| Secondary | pH | Baseline, 30, 60, 90, and 120 minutes after supplement ingestion, 5 minutes after the first Wingate test, 5, 10, and 15 minutes after the second Wingate test | ClinicalTrials.gov | |
| Secondary | Total Gastrointestinal Symptom Score | Baseline, 60, and 120 minutes after supplement ingestion, 15 minutes, 2, 4 and 6 hours after the second Wingate test at each intervention visit (within 2 weeks of the first intervention visit) | Total gastrointestinal symptom severity was assessed using a symptom rating questionnaire. The total score was calculated by summing individual symptom severity ratings, with higher scores indicating more severe gastrointestinal symptoms. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)