REstoration of Communication and LAnguage With Intracortical Microelectrodes
NCT07933549, Not applicable, Not yet recruiting, The University of Texas Health Science Center, Houston
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | REstoration of Communication and LAnguage With Intracortical Microelectrodes | ClinicalTrials.gov |
| NCT number | NCT07933549 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 4 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | The University of Texas Health Science Center, Houston | ClinicalTrials.gov |
| Conditions | Amyotrophic Lateral Sclerosis (ALS), locked-in Syndrome, Brain Injury, Stroke | ClinicalTrials.gov |
| Interventions | RECLAIM System | ClinicalTrials.gov |
| First posted | 2026-11-12 | ClinicalTrials.gov |
| Last updated | 2026-11-12 | ClinicalTrials.gov |
Registered outcomes 7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Safety as assessed by the number and type of adverse events that occur | From time of implant to one year post-implant | ClinicalTrials.gov | |
| Secondary | Safety as assessed by the number of participants with device explanted | From time of implant to one year post-implant | ClinicalTrials.gov | |
| Secondary | Safety as assessed by the number of participants with Serious Adverse Events that result in death or permanently increased disability | From time of implant to one year post-implant | ClinicalTrials.gov | |
| Secondary | Effectiveness of the device as assessed by the Word error rate (WER) | Every three months for the first two years post-implant | ClinicalTrials.gov | |
| Secondary | Effectiveness of device as assessed by the Phoneme error rate (PER) | Every three months for the first two years post-implant | ClinicalTrials.gov | |
| Secondary | Effectiveness of the device as assessed by the Bilingual Evaluation Understudy (BLEU) Score | Every three months for the first two years post-implant | BLEU (Bilingual Evaluation Understudy) quantifies, on a range of 0-1, the overlap between the decoded text and the reference text based on matching n-grams. Higher BLEU scores indicate that the decoded output more closely matches the reference at the level of local word sequences. | ClinicalTrials.gov |
| Secondary | Effectiveness of the device as assessed by the Bidirectional Encoder Representations from Transformers (BERT) Score | Every three months for the first two years post-implant | BERT Score compares the semantic similarity (on a range of -1 to 1) between the decoded text sequence and the reference text using a pretrained language model (BERT). Higher scores indicated stronger semantic alignment. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)