Hybrid Parasternal Intercostal Plane Block Versus No Block for Postoperative Analgesia After Cardiac Surgery Via Median Sternotomy
NCT07934290, Not applicable, Not yet recruiting, Seo-hee Lee
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Hybrid Parasternal Intercostal Plane Block Versus No Block for Postoperative Analgesia After Cardiac Surgery Via Median Sternotomy | ClinicalTrials.gov |
| NCT number | NCT07934290 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 172 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Seo-hee Lee | ClinicalTrials.gov |
| Conditions | Valve Disease, Heart, Coronary Artery Disease, Aorta Disease | ClinicalTrials.gov |
| Interventions | Hybrid parasternal intercostal plane block (HPIP) | ClinicalTrials.gov |
| First posted | 2026-11-12 | ClinicalTrials.gov |
| Last updated | 2026-11-12 | ClinicalTrials.gov |
Registered outcomes 13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Pain score on coughing at 12 hours after surgery | 12 hours after the end of surgery | Pain intensity during a standardized cough, measured on the Numeric Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst imaginable pain); higher scores indicate worse pain. Assessed 12 hours after the end of surgery (allowable window ±2 hours) by ICU nurses blinded to group allocation. | ClinicalTrials.gov |
| Secondary | Pain score at rest | 12 and 24 hours after the end of surgery | Pain intensity at rest, measured on the Numeric Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst imaginable pain); higher scores indicate worse pain. | ClinicalTrials.gov |
| Secondary | Pain score on coughing at 24 hours | 24 hours after the end of surgery | Pain intensity during a standardized cough, measured on the Numeric Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst imaginable pain); higher scores indicate worse pain. | ClinicalTrials.gov |
| Secondary | Cumulative opioid consumption | 0-12 and 0-24 hours after the end of surgery | Total postoperative opioid consumption (IV-PCA fentanyl and rescue opioids) converted to morphine milligram equivalents (MME, mg) | ClinicalTrials.gov |
| Secondary | Intraoperative opioid consumption | From block performance to initiation of cardiopulmonary bypass | Total intraoperative fentanyl dose (mcg/kg) | ClinicalTrials.gov |
| Secondary | Time to first rescue analgesia | From the end of surgery until the first administration of a rescue analgesic, assessed up to 48 hours | Time (hours) from the end of surgery to the first administration of a rescue analgesic. Participants who do not receive rescue analgesia within 48 hours will be censored at 48 hours. | ClinicalTrials.gov |
| Secondary | Time to extubation | From the end of surgery until tracheal extubation, assessed up to 7 days | Time (hours) from the end of surgery to tracheal extubation. | ClinicalTrials.gov |
| Secondary | ICU length of stay | Up to 30 days after surgery | Duration (days) from ICU admission to ICU discharge. | ClinicalTrials.gov |
| Secondary | Hospital length of stay | Up to 30 days after surgery | Duration (days) from the day of surgery to hospital discharge. Participants still hospitalized at 30 days will be recorded as 30 days. | ClinicalTrials.gov |
| Other | Incidence of block-related complications | Up to 30 days after surgery | Number of participants with pneumothorax, hemothorax, clinically significant hematoma, nerve injury, injection-site infection, or local anesthetic systemic toxicity, assessed from block performance up to 30 days after surgery. | ClinicalTrials.gov |
| Other | Incidence of opioid-related adverse events | 0, 6, 12, 24, and 48 hours after surgery | Number of participants with postoperative nausea and vomiting (PONV) or urinary retention | ClinicalTrials.gov |
| Other | Ease of block performance | Immediately after block performance | Anesthesiologist-rated ease of block performance on a 5-point Likert scale (1 = very difficult, 5 = very easy) | ClinicalTrials.gov |
| Other | Block procedure time | Immediately after block performance | Time required to complete the bilateral block (minutes) | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)