Cell line · CVCL_0035

PC-3

Cancer cell line, Homo sapiens. Prostate carcinoma. 364 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. PC-3. Cell lines, record CVCL_0035. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0035

On this page

Cell line

As Cellosaurus gives it.

Name: PC-3
Accession: CVCL_0035
RRID: RRID:CVCL_0035
Synonyms: PC3, PC.3
Species: Homo sapiens (Human)
Sex: Male
Age at sampling: 62Y
Category: Cancer cell line
Diseases: Prostate carcinoma (NCIt C4863)
Derived from: Bone (metastatic)
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems1

Problem	Cellosaurus's note
Caution	There seem to be two distinct cell lines which were assigned NCBI_Iran catalog number C427.

Source Cellosaurus

Papers364

2 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.

Paper	Journal	Year	How we know	Source
SRSF1 coordinates transcription and alternative splicing to modulate p53 and apoptosis.	bioRxiv	2026	Its Methods give the RRID and name the line	PubMed
In vivo validation of intramolecular bivalent glues targeting PSMA reveals potent and tissue-selective BRD4 degradation in prostate cancer.	Acta Pharm Sin B	2026	Its Methods give the RRID and name the line	PubMed
Design of Potent, Non-Toxic Antimicrobial Agents Derived from the Frog Skin Peptide Raniseptin-PL Active Against Gram-Negative ESKAPE+ Pathogens.	Antibiotics (Basel)	2026	Its Methods give the RRID and name the line	PubMed
Primary tumor-derived lactate primes prostate cancer cells for a dormant fate.	Sci Adv	2026	Its Methods give the RRID and name the line	PubMed
Berberine and Etoposide Exert Synergistic Anticancer Effects in A431 Epidermoid Carcinoma Cells.	ACS Omega	2026	Its Methods give the RRID and name the line	PubMed
Physicochemical Characterisation and In Vitro Bioactivity of Sumac (Rhus coriaria)-Derived Exosome-Like Nanoparticles.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed
Prostate Cancer Patient-Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)-Based Personalized Therapy.	Adv Healthc Mater	2026	Its Methods give the RRID and name the line	PubMed
Phytochemical Analysis Using LC-MS/MS and Anticancer Activity of Asphodelus tenuifolius Roots: Cell Cycle Arrest, Apoptosis, and In Silico Insights.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed
Combination of PARP inhibitor olaparib and a vascular disrupting agent reduces tumor growth in a preclinical model of prostate cancer.	Cancer Chemother Pharmacol	2026	Its Methods give the RRID and name the line	PubMed
Nutrient deprivation enhances the cytotoxic effects of a sulfonamide-chalcone hybrid in PC-3 prostate cancer cells.	Mol Cell Biochem	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 364

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Relatives240

Relation	Cell line	Accession	Problem	Source
Derived from it	1-LN	CVCL_L211		Cell lines
Derived from it	ALVA-101	CVCL_4735	Has a recorded problem	Cell lines
Derived from it	ALVA-31	CVCL_4737	Has a recorded problem	Cell lines
Derived from it	ALVA-41	CVCL_4734	Has a recorded problem	Cell lines
Derived from it	ALVA-55	CVCL_4736	Has a recorded problem	Cell lines
Derived from it	Abcam PC-3 AATF KO	CVCL_C6Y9		Cell lines
Derived from it	Abcam PC-3 ABCB1 KO	CVCL_C6YA		Cell lines
Derived from it	Abcam PC-3 ABL1 KO	CVCL_C6YB		Cell lines
Derived from it	Abcam PC-3 ADGRG1 KO	CVCL_C6YC		Cell lines
Derived from it	Abcam PC-3 AGTR1 KO	CVCL_C6YD		Cell lines

1 to 10 of 240

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Cell banks22

Cell bank	Catalog number	Status	Source
ATCC	CRL-1435		ATCC
ATCC	CRL-7934	Discontinued	Cellosaurus
Abcam	ab275472		Abcam
AddexBio	C0019002/61		Cellosaurus
BCRC	60122		BCRC
BCRJ	0269		BCRJ
CCTCC	GDC0095		Cellosaurus
CLS	300312		CLS
DSMZ	ACC-465		DSMZ
ECACC	90112714		ECACC

1 to 10 of 22

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0035

GET https://conductscience.org/api/cell-lines/v1/CVCL_0035/papers?page=2

API reference For AI assistants