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Cell line · CVCL_4734

ALVA-41

Cancer cell line, Homo sapiens. Prostate carcinoma. Cellosaurus records it as contaminated. 8 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. ALVA-41. Cell lines, record CVCL_4734. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_4734

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Cell line

As Cellosaurus gives it.

Name
ALVA-41
Accession
CVCL_4734
RRID
RRID:CVCL_4734
Synonyms
ALVA 41, ALVA41, American Lake VA-41
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
62Y
Category
Cancer cell line
Diseases
Prostate carcinoma (NCIt C4863)
Derived from
Bone (metastatic)
Parent
PC-3 (CVCL_0035)
Entry created
2012-04-04
Entry updated
2025-04-10

Source Cellosaurus

Problems1

ProblemCellosaurus's note
Contaminated
Shown to be a PC-3 derivative (PubMed=11304728; PubMed=20143388; CelloPub=CLPUB00698). Originally thought to originate from the bone metastasis in a patient with well differentiated, stage B2, adenocarcinoma of the prostate.

Papers8

PaperJournalYearHow we knowRetractedSource
Check your cultures! A list of cross-contaminated or misidentified cell lines.Int J Cancer2010Cellosaurus cites itPubMed
Cell lines used in prostate cancer research: a compendium of old and new lines--part 1.J Urol2005Cellosaurus cites itPubMed
Models for prostate cancer. Molecular characterization and critical appraisal of human prostate carcinoma cell lines.2004Cellosaurus cites itCellosaurus
Human prostate cancer cell lines.Methods Mol Med2003Cellosaurus cites itPubMed
Widely used prostate carcinoma cell lines share common origins.Prostate2001Cellosaurus cites itPubMed
Gap-junctional communication in normal and neoplastic prostate epithelial cells and its regulation by cAMP.Mol Carcinog1996Cellosaurus cites itPubMed
Characterization of ALVA-41 cells, a new human prostatic cancer cell line.Steroids1994Cellosaurus cites itPubMed
Effects of sex hormone binding globulin (SHBG) on human prostatic carcinoma.J Steroid Biochem Mol Biol1991Cellosaurus cites itPubMed

Relatives1

RelationCell lineAccessionProblem
ParentPC-3CVCL_0035

Source Cell lines

Cell banks0

None in this release.

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_4734

GET https://conductscience.org/api/cell-lines/v1/CVCL_4734/problems