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Cell line · CVCL_0179

BT-474

Cancer cell line, Homo sapiens. Invasive breast carcinoma of no special type. 172 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. BT-474. Cell lines, record CVCL_0179. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0179

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Cell line

As Cellosaurus gives it.

Name
BT-474
Accession
CVCL_0179
RRID
RRID:CVCL_0179
Synonyms
Bt-474, BT474
Species
Homo sapiens (Human)
Sex
Female
Age at sampling
60Y
Category
Cancer cell line
Diseases
Invasive breast carcinoma of no special type (NCIt C4194)
Derived from
Breast (in situ)
Entry created
2012-04-04
Entry updated
2026-03-31

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers172

PaperJournalYearHow we knowRetractedSource
Impact of Trastuzumab and Pertuzumab on HER2 Localization and the Estrogen Receptor Cistrome in ER+/HER2+ Breast Cancer.bioRxiv2026Its Methods give the RRID and name the linePubMed
The role of autoproteolysis and mitoribosomal proteins in the regulation of the mitochondrial LACTB tumor suppressor.EMBO Rep2026Its Methods give the RRID and name the linePubMed
Targeting CD24 Activates Macrophages to Reduce Tumor Burden in Preclinical Models of Solid Tumors.Clin Cancer Res2026Its Methods give the RRID and name the linePubMed
Targetable S100-RAGE Signaling Mediates Intrinsic Trastuzumab Deruxtecan Resistance in Metastatic Breast Cancer.Clin Cancer Res2026Its Methods give the RRID and name the linePubMed
Targeted antibody-drug conjugates for rhabdomyosarcoma and other FGFR4-expressing cancers.Cell Rep Med2026Its Methods give the RRID and name the linePubMed
Distinct metabolic dependency on BCAA defines cancer stemness and malignancy in human triple-negative breast cancer.Cell Rep2026Its Methods give the RRID and name the linePubMed
Single-Cell and Multiomics Characterization of p21 in Cancer Progression and Therapeutic Sensitivity.Hum Mutat2026Its Methods give the RRID and name the linePubMed
Engineering Cathepsin S Selective Chemical Probes and Antibody-Drug Conjugates through Substrate Profiling with Unnatural Amino Acids.J Med Chem2026Its Methods give the RRID and name the linePubMed
Combined inhibition of PLK4 and PPM1D promotes cell death in cancer cells with 17q amplification.Cancer Cell Int2026Its Methods give the RRID and name the linePubMed
Hydrostatic pressure activates HIF-1α via β-catenin to promote stemness in breast cancer cells.FEBS Open Bio2026Its Methods give the RRID and name the linePubMed

1 to 10 of 172

See all 172 papers

Relatives15

RelationCell lineAccessionProblemSource
Derived from itBT-474 Clone 5CVCL_AQ07Cell lines
Derived from itBT-474 EEICVCL_AR96Cell lines
Derived from itBT-474 Ecadherin EmGFPCVCL_A4CLCell lines
Derived from itBT-474 Tam1CVCL_AR86Cell lines
Derived from itBT-474 Tam2CVCL_A4AKCell lines
Derived from itBT-474-Luc2CVCL_C9CUCell lines
Derived from itBT-474/CMV-LucCVCL_4Y08Cell lines
Derived from itBT-474c1CVCL_IP20Cell lines
Derived from itBT474 A3CVCL_YX79Cell lines
Derived from itBT474-5FU[r]CVCL_4V65Cell lines

1 to 10 of 15

See all 15 relatives

Cell banks13

Cell bankCatalog numberStatusSource
ATCCCRL-7913DiscontinuedCellosaurus
ATCCHTB-20ATCC
AddexBioC0006012/4902Cellosaurus
BCRC60359BCRC
BCRJ0353BCRJ
CLS300131CLS
DSMZACC-64DSMZ
HysigenTCH-C139Hysigen
IBRCC10140Cellosaurus
ICLCHTL00008ICLC

1 to 10 of 13

See all 13 cell banks

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0179

GET https://conductscience.org/api/cell-lines/v1/CVCL_0179/papers?page=2

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