Cell line · CVCL_0284
H4-II-E
Cancer cell line, Rattus norvegicus. Rat hepatocellular carcinoma. 6 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. H4-II-E. Cell lines, record CVCL_0284. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0284
On this page
Cell line
As Cellosaurus gives it.
- Name
- H4-II-E
- Accession
- CVCL_0284
- RRID
- RRID:CVCL_0284
- Synonyms
- H-4-II-E, H4IIE
- Species
- Rattus norvegicus (Rat)
- Sex
- Male
- Age at sampling
- Age unspecified
- Category
- Cancer cell line
- Diseases
- Rat hepatocellular carcinoma (NCIt C60416)
- Derived from
- Liver (in situ)
- Parent
- H4-II (CVCL_4623)
- Entry created
- 2012-04-04
- Entry updated
- 2025-11-27
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers6
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| Assessment of distinct effects of Parinari curatellifolia Planch.ex Benth Ethanolic leaf extract on glucose transport in different cell types. | PeerJ | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Tissue-specific expression differences in Ras-related GTP-binding proteins in male rats. | Physiol Rep | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Identification of Putative Receptors for the Novel Adipokine CTRP3 Using Ligand-Receptor Capture Technology. | PLoS One | 2016 | Its Methods give the RRID and name the line | PubMed | |
| Induction of enzyme activity in cell culture: a rapid screen for detection of planar polychlorinated organic compounds. | J Assoc Off Anal Chem | 1979 | Cellosaurus cites it | PubMed | |
| Properties of the H-4-II-E tumor cell system. I. Growth and cell proliferation kinetics of an experimental hepatoma. | Cell Tissue Kinet | 1977 | Cellosaurus cites it | PubMed | |
| HEPATOMAS IN TISSUE CULTURE COMPARED WITH ADAPTING LIVER IN VIVO. | Natl Cancer Inst Monogr | 1964 | Cellosaurus cites it | PubMed |
Relatives6
| Relation | Cell line | Accession | Problem | Source |
|---|---|---|---|---|
| Parent | H4-II | CVCL_4623 | Cell lines | |
| Derived from it | H4-II-E-C3 | CVCL_0285 | Cell lines | |
| Derived from it | H4G1.1c2 | CVCL_DC26 | Cell lines | |
| Derived from it | H4L1.1c4 | CVCL_DC27 | Cell lines | |
| Derived from it | H4L7.5c2 | CVCL_DC28 | Cell lines | |
| Derived from it | HL1C | CVCL_D052 | Cell lines |
Cell banks8
| Cell bank | Catalog number | Status | Source |
|---|---|---|---|
| ATCC | CRL-1548 | ATCC | |
| BCRC | 60209 | BCRC | |
| CCTCC | GDC0104 | Cellosaurus | |
| CLS | 305204 | Discontinued | Cellosaurus |
| ECACC | 87031301 | ECACC | |
| IZSLER | BS TCL 136 | Cellosaurus | |
| KCB | KCB 200819YJ | Cellosaurus | |
| KCLB | 21548 | KCLB |
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_0284
GET https://conductscience.org/api/cell-lines/v1/CVCL_0284/problems