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Cell line · CVCL_4623

H4-II

Cancer cell line, Rattus norvegicus. Rat hepatocellular carcinoma. 2 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. H4-II. Cell lines, record CVCL_4623. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_4623

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Cell line

As Cellosaurus gives it.

Name
H4-II
Accession
CVCL_4623
RRID
RRID:CVCL_4623
Synonyms
H4II, H-35tc2, Reuber-H-35 hepatoma tissue culture 2, Reuber H-35 tc2, Reuber H35 tc2, H-35 Reuber tc2, H35 Reuber tc2, RH-35 tc2, RH35 tc2, H-35 tc2, H35 tc2
Species
Rattus norvegicus (Rat)
Sex
Male
Age at sampling
Age unspecified
Category
Cancer cell line
Diseases
Rat hepatocellular carcinoma (NCIt C60416)
Derived from
Liver (in situ)
Entry created
2012-04-04
Entry updated
2025-11-27

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers2

PaperJournalYearHow we knowRetractedSource
Induction of enzyme activity in cell culture: a rapid screen for detection of planar polychlorinated organic compounds.J Assoc Off Anal Chem1979Cellosaurus cites itPubMed
Properties of the H-4-II-E tumor cell system. I. Growth and cell proliferation kinetics of an experimental hepatoma.Cell Tissue Kinet1977Cellosaurus cites itPubMed

Relatives4

RelationCell lineAccessionProblemSource
Derived from itH4-II-ECVCL_0284Cell lines
Derived from itHyCyte H4-II KO-rInsrrCVCL_E1JWCell lines
Derived from itHyCyte H4-II stable cell line for rInsrr overexpressionCVCL_F4SYCell lines
From the same personH4AzC2CVCL_X358Cell lines

Cell banks2

Cell bankCatalog numberStatusSource
CLS305210CLS
ECACC89042702ECACC

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_4623

GET https://conductscience.org/api/cell-lines/v1/CVCL_4623/problems