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Cell line · CVCL_0535

SNB-19

Cancer cell line, Homo sapiens. Astrocytoma. Cellosaurus records it as contaminated. 39 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. SNB-19. Cell lines, record CVCL_0535. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0535

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Cell line

As Cellosaurus gives it.

Name
SNB-19
Accession
CVCL_0535
RRID
RRID:CVCL_0535
Synonyms
SNB.19, SNB19, Surgical Neurology Branch-19
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
75Y
Category
Cancer cell line
Diseases
Astrocytoma (NCIt C60781); Astrocytoma (ORDO Orphanet_94)
Derived from
Brain, parietal lobe (in situ)
Parent
U-251MG (CVCL_0021)
Entry created
2012-04-04
Entry updated
2026-06-25

Source Cellosaurus

Problems1

ProblemCellosaurus's note
ContaminatedShown to be a U-251MG derivative (PubMed=18304946; PubMed=20143388; PubMed=22570425). Originally thought to originate from a 47 year old patient with a left parieto-occipital glioblastoma.

Papers39

PaperJournalYearHow we knowRetractedSource
COVID-19-associated neuroinflammation and astrocyte death in the brain linked to ORF3a-induced activation of Sur1-mediated ion channels.mBio2025Its Methods give the RRID and name the linePubMed
HTS384 NCI60: The Next Phase of the NCI60 Screen.Cancer Res2024Cellosaurus cites it, and its Methods give the RRID and name the linePubMed
Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen-specific tumor cell killing by cytotoxic T cells.Elife2023Its Methods give the RRID and name the linePubMed
Calpain-mediated cleavage generates a ZBTB18 N-terminal product that regulates HIF1A signaling and glioblastoma metabolism.iScience2022Its Methods give the RRID and name the linePubMed
Small-Molecule NSC59984 Induces Mutant p53 Degradation through a ROS-ERK2-MDM2 Axis in Cancer Cells.Mol Cancer Res2022Its Methods give the RRID and name the linePubMed
HIV-1 Vpr-Induced Proinflammatory Response and Apoptosis Are Mediated through the Sur1-Trpm4 Channel in Astrocytes.mBio2020Its Methods give the RRID and name the linePubMed
Quantitative Proteomics of the Cancer Cell Line Encyclopedia.Cell2020Cellosaurus cites itPubMed
Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines.iScience2019Cellosaurus cites itPubMed
Next-generation characterization of the Cancer Cell Line Encyclopedia.Nature2019Cellosaurus cites itPubMed
An Interactive Resource to Probe Genetic Diversity and Estimated Ancestry in Cancer Cell Lines.Cancer Res2019Cellosaurus cites itPubMed

1 to 10 of 39

See all 39 papers

Relatives1

RelationCell lineAccessionProblem
ParentU-251MGCVCL_0021

Source Cell lines

Cell banks5

Cell bankCatalog numberStatusSource
ATCCCRL-2219DiscontinuedCellosaurus
CLS305492CLS
DSMZACC-325DSMZ
JCRBNIHS0294DiscontinuedCellosaurus
NCI-DCTDSNB-19Cellosaurus

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0535

GET https://conductscience.org/api/cell-lines/v1/CVCL_0535/papers?page=2