Cell line · CVCL_1275
D425 Med
Cancer cell line, Homo sapiens. Medulloblastoma, non-WNT/non-SHH, group 3. 31 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. D425 Med. Cell lines, record CVCL_1275. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1275
On this page
Cell line
As Cellosaurus gives it.
- Name
- D425 Med
- Accession
- CVCL_1275
- RRID
- RRID:CVCL_1275
- Synonyms
- D-425 Med, D-425 Med-C, D-425MED, D425_Med, D425MED, D425Med, Med 425, D-425, D425, H425
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 6Y
- Category
- Cancer cell line
- Diseases
- Medulloblastoma, non-WNT/non-SHH, group 3 (NCIt C129445); Medulloblastoma (ORDO Orphanet_616)
- Derived from
- Brain, posterior fossa (in situ)
- Entry created
- 2012-04-04
- Entry updated
- 2025-04-10
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers31
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| A Conserved Enhancer Locus in Extrachromosomal DNA and Homogeneously Staining Regions Activates MYC Transcription in Group 3 Medulloblastoma. | Cancer Res | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Meningeal-tumor interactions define distinct modes of leptomeningeal colonization in Group 3 medulloblastoma. | Acta Neuropathol Commun | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Single-cell multi-omics identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastoma. | Nat Commun | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function. | Nat Commun | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy. | Cancer Res | 2025 | Its Methods give the RRID and name the line | PubMed | |
| B7-H3 CAR T Cells Are Effective against Ependymomas but Limited by Tumor Size and Immune Response. | Clin Cancer Res | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Single-cell multi-omics analysis identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastoma | Res Sq | 2024 | Its Methods give the RRID and name the line | PubMed | |
| The OTX2 Gene Induces Tumor Growth and Triggers Leptomeningeal Metastasis by Regulating the mTORC2 Signaling Pathway in Group 3 Medulloblastomas. | Int J Mol Sci | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Combination drug screen identifies synergistic drug interaction of BCL-XL and class I histone deacetylase inhibitors in MYC-amplified medulloblastoma cells. | J Neurooncol | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma. | Mol Cell | 2024 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 31
See all 31 papersRelatives1
| Relation | Cell line | Accession | Problem |
|---|---|---|---|
| From the same person | D458 Med | CVCL_1161 |
Source Cell lines
Cell banks1
| Cell bank | Catalog number | Status |
|---|---|---|
| Millipore | SCC290 |
Source Millipore
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_1275
GET https://conductscience.org/api/cell-lines/v1/CVCL_1275/papers?page=2