Cell line · CVCL_1161
D458 Med
Cancer cell line, Homo sapiens. Medulloblastoma, non-WNT/non-SHH, group 3. 21 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. D458 Med. Cell lines, record CVCL_1161. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1161
On this page
Cell line
As Cellosaurus gives it.
- Name
- D458 Med
- Accession
- CVCL_1161
- RRID
- RRID:CVCL_1161
- Synonyms
- D-458 Med, D-458MED, D458MED, D458Med, Med 458, D-458, D458
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 6-7Y
- Category
- Cancer cell line
- Diseases
- Medulloblastoma, non-WNT/non-SHH, group 3 (NCIt C129445); Medulloblastoma (ORDO Orphanet_616)
- Derived from
- Cerebrospinal fluid (in situ)
- Entry created
- 2012-04-04
- Entry updated
- 2025-04-10
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers21
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| A Conserved Enhancer Locus in Extrachromosomal DNA and Homogeneously Staining Regions Activates MYC Transcription in Group 3 Medulloblastoma. | Cancer Res | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Transcriptional regulation of protein synthesis by mediator kinase represents a therapeutic vulnerability in MYC-driven medulloblastoma. | Nat Commun | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Single-cell multi-omics identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastoma. | Nat Commun | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth. | Nat Cell Biol | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Single-cell multi-omics analysis identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastoma | Res Sq | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Transcriptional Regulation of Protein Synthesis by Mediator Kinase Represents a Therapeutic Vulnerability in MYC-driven Medulloblastoma | Res Sq | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma. | Mol Cell | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Integrin-αvβ3 is a Therapeutically Targetable Fundamental Factor in Medulloblastoma Tumorigenicity and Radioresistance. | Cancer Res Commun | 2023 | Its Methods give the RRID and name the line | PubMed | |
| Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma. | bioRxiv | 2023 | Its Methods give the RRID and name the line | PubMed | |
| Antiangiogenic Compound Axitinib Demonstrates Low Toxicity and Antitumoral Effects against Medulloblastoma. | Cancers (Basel) | 2021 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 21
See all 21 papersRelatives1
| Relation | Cell line | Accession | Problem |
|---|---|---|---|
| From the same person | D425 Med | CVCL_1275 |
Source Cell lines
Cell banks0
None in this release.
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_1161
GET https://conductscience.org/api/cell-lines/v1/CVCL_1161/papers?page=2