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Cell line · CVCL_1386

LS513

Cancer cell line, Homo sapiens. Cecum adenocarcinoma. 43 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. LS513. Cell lines, record CVCL_1386. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1386

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Cell line

As Cellosaurus gives it.

Name
LS513
Accession
CVCL_1386
RRID
RRID:CVCL_1386
Synonyms
LS-513, LS 513
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
63Y
Category
Cancer cell line
Diseases
Cecum adenocarcinoma (NCIt C5543)
Derived from
Intestine, ileocecal valve (in situ)
Entry created
2012-04-04
Entry updated
2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers43

PaperJournalYearHow we knowRetractedSource
RNF43 p.G659fs leads to natural killer cell dysfunction in MSI-high colorectal cancer through PI3K/AKT/mTOR signaling and HLA-E up-regulation.Sci Adv2026Its Methods give the RRID and name the linePubMed
Variant-Specific Landscape of Mutual Exclusivity Among BRAF, EGFR, and KRAS Oncogenes Reveals Overlap With Functionally Antagonistic Mutant Pairs.Int J Cancer2026Its Methods give the RRID and name the linePubMed
High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRASG12D colorectal cancer.NPJ Precis Oncol2026Its Methods give the RRID and name the linePubMed
L1TD1 promotes colorectal mucinous adenocarcinoma progression by enhancing ABCC3 mRNA stability.Oncogene2026Its Methods give the RRID and name the linePubMed
Preclinical Characterization and Clinical Activity of RNK08954, a Highly Selective and Orally Bioavailable KRASG12D Inhibitor.Cancer Discov2026Its Methods give the RRID and name the linePubMed
Overcoming multidrug resistance in gastrointestinal cancers with a CDH17-targeted ADC conjugated to a DNA topoisomerase inhibitor.Cell Rep Med2025Its Methods give the RRID and name the linePubMed
Clonal dispersal is associated with tumor heterogeneity and poor prognosis in colorectal cancer.iScience2025Its Methods give the RRID and name the linePubMed
Glecirasib, a Potent and Selective Covalent KRAS G12C Inhibitor Exhibiting Synergism with Cetuximab or SHP2 Inhibitor JAB-3312.Cancer Res Commun2025Its Methods give the RRID and name the linePubMed
Direct Inhibition of RAS Reveals the Features of Oncogenic Signaling Driven by RAS G12 and Q61 Mutations.Cancer Discov2025Its Methods give the RRID and name the linePubMed
Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases.Cell Rep Med2024Its Methods give the RRID and name the linePubMed

1 to 10 of 43

See all 43 papers

Relatives1

RelationCell lineAccessionProblem
Derived from itSNU-1958CVCL_T040Has a recorded problem

Source Cell lines

Cell banks4

Cell bankCatalog numberStatusSource
ATCCCRL-2134ATCC
CLS300457CLS
HysigenTCH-C241Hysigen
KCLB22134KCLB

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_1386

GET https://conductscience.org/api/cell-lines/v1/CVCL_1386/papers?page=2