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Cell line · CVCL_1386

Papers43

PaperJournalYearHow we knowRetractedSource
RNF43 p.G659fs leads to natural killer cell dysfunction in MSI-high colorectal cancer through PI3K/AKT/mTOR signaling and HLA-E up-regulation.Sci Adv2026Its Methods give the RRID and name the linePubMed
Variant-Specific Landscape of Mutual Exclusivity Among BRAF, EGFR, and KRAS Oncogenes Reveals Overlap With Functionally Antagonistic Mutant Pairs.Int J Cancer2026Its Methods give the RRID and name the linePubMed
High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRASG12D colorectal cancer.NPJ Precis Oncol2026Its Methods give the RRID and name the linePubMed
L1TD1 promotes colorectal mucinous adenocarcinoma progression by enhancing ABCC3 mRNA stability.Oncogene2026Its Methods give the RRID and name the linePubMed
Preclinical Characterization and Clinical Activity of RNK08954, a Highly Selective and Orally Bioavailable KRASG12D Inhibitor.Cancer Discov2026Its Methods give the RRID and name the linePubMed
Overcoming multidrug resistance in gastrointestinal cancers with a CDH17-targeted ADC conjugated to a DNA topoisomerase inhibitor.Cell Rep Med2025Its Methods give the RRID and name the linePubMed
Clonal dispersal is associated with tumor heterogeneity and poor prognosis in colorectal cancer.iScience2025Its Methods give the RRID and name the linePubMed
Glecirasib, a Potent and Selective Covalent KRAS G12C Inhibitor Exhibiting Synergism with Cetuximab or SHP2 Inhibitor JAB-3312.Cancer Res Commun2025Its Methods give the RRID and name the linePubMed
Direct Inhibition of RAS Reveals the Features of Oncogenic Signaling Driven by RAS G12 and Q61 Mutations.Cancer Discov2025Its Methods give the RRID and name the linePubMed
Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases.Cell Rep Med2024Its Methods give the RRID and name the linePubMed
The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells.Sci Signal2022Its Methods give the RRID and name the linePubMed
Pan-cancer proteomic map of 949 human cell lines.Cancer Cell2022Cellosaurus cites itPubMed
RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.Nat Commun2022Its Methods give the RRID and name the linePubMed
Quantitative Proteomics of the Cancer Cell Line Encyclopedia.Cell2020Cellosaurus cites itPubMed
Next-generation characterization of the Cancer Cell Line Encyclopedia.Nature2019Cellosaurus cites itPubMed
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.Nature2019Cellosaurus cites itPubMed
An Interactive Resource to Probe Genetic Diversity and Estimated Ancestry in Cancer Cell Lines.Cancer Res2019Cellosaurus cites itPubMed
Differential Effector Engagement by Oncogenic KRAS.Cell Rep2018Cellosaurus cites itPubMed
Pharmacoproteomic characterisation of human colon and rectal cancer.Mol Syst Biol2017Cellosaurus cites itPubMed
Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells.Cell Rep2017Cellosaurus cites itPubMed

cell-lines-2026-11-14-0.1.0

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
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  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

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