Cell line · CVCL_2219
U-373MG ATCC
Cancer cell line, Homo sapiens. Astrocytoma. Cellosaurus records it as misidentified/contaminated. 41 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. U-373MG ATCC. Cell lines, record CVCL_2219. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_2219
On this page
Cell line
As Cellosaurus gives it.
- Name
- U-373MG ATCC
- Accession
- CVCL_2219
- RRID
- RRID:CVCL_2219
- Synonyms
- U-373MG, U373 MG, U-373-MG, U-373 MG, U373-MG, U373MG, U373, 373 MG, 373MG
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 75Y
- Category
- Cancer cell line
- Diseases
- Astrocytoma (NCIt C60781); Astrocytoma (ORDO Orphanet_94)
- Derived from
- Brain, parietal lobe (in situ)
- Parent
- U-251MG (CVCL_0021)
- Entry created
- 2012-04-04
- Entry updated
- 2025-04-10
Source Cellosaurus
Problems1
| Problem | Cellosaurus's note |
|---|---|
| Misidentified/contaminated | Shown to be a U-251MG derivative. This cell line is not the original astrocytoma cell line established in 1973 at the University of Uppsala. See U-373MG Uppsala (Cellosaurus=CVCL_2818) for the original U-373MG cell line. |
Source Cellosaurus
Papers41
2 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| Cell Settling, Migration, and Stochastic Cancer Gene Expression Suggest Potassium Membrane Flux May Initiate pH Reversal. | Biomolecules | 2025 | Its Methods give the RRID and name the line | PubMed | |
| The anti-aging Klotho protects glioblastoma macrophages from radiotherapy-induced inflammation and predicts immunotherapy response. | Int J Cancer | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Transcriptional repression of SOX2 by p53 in cancer cells regulates cell identity and migration. | Int J Cancer | 2025 | Its Methods give the RRID and name the line | PubMed | |
| A Checkpoint Reversal Receptor Mediates Bipartite Activation and Enhances CAR T-cell Function. | Cancer Res Commun | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Glioblastoma-derived migrasomes promote migration and invasion by releasing PAK4 and LAMA4. | Commun Biol | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Functional loss of ERBB receptor feedback inhibitor 1 (MIG6) promotes glioblastoma tumorigenesis by aberrant activation of epidermal growth factor receptor (EGFR). | Mol Oncol | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Targeting Retinaldehyde Dehydrogenases to Enhance Temozolomide Therapy in Glioblastoma. | Int J Mol Sci | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Identification of a strong genetic risk factor for major depressive disorder in the human virome. | iScience | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Mieap forms membrane-less organelles involved in cardiolipin metabolism. | iScience | 2024 | Its Methods give the RRID and name the line | PubMed | |
| STAT6 in mitochondrial outer membrane impairs mitochondrial fusion by inhibiting MFN2 dimerization. | iScience | 2022 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 41
See all 41 papersRelatives2
| Relation | Cell line | Accession | Problem | Source |
|---|---|---|---|---|
| Parent | U-251MG | CVCL_0021 | Cell lines | |
| Derived from it | U373-CD4 | CVCL_E8AN | Cell lines |
Cell banks7
| Cell bank | Catalog number | Status | Source |
|---|---|---|---|
| ATCC | HTB-17 | Discontinued | Cellosaurus |
| CCLV | CCLV-RIE 0675 | Cellosaurus | |
| ECACC | 89081403 | Discontinued | Cellosaurus |
| IZSLER | BS TCL 89 | Cellosaurus | |
| JCRB | NIHS0295 | Discontinued | Cellosaurus |
| KCLB | 30017 | KCLB | |
| NCBI_Iran | C455 | Cellosaurus |
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_2219
GET https://conductscience.org/api/cell-lines/v1/CVCL_2219/papers?page=2