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Cell line · CVCL_8442

MOBS-1

Cancer cell line, Homo sapiens. Adult acute monocytic leukemia. Cellosaurus records it as contaminated. 4 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. MOBS-1. Cell lines, record CVCL_8442. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_8442

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Cell line

As Cellosaurus gives it.

Name
MOBS-1
Accession
CVCL_8442
RRID
RRID:CVCL_8442
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
37Y
Category
Cancer cell line
Diseases
Adult acute monocytic leukemia (NCIt C8263); Acute monoblastic/monocytic leukemia (ORDO Orphanet_514)
Derived from
Pleural effusion (in situ)
Parent
U-937 (CVCL_0007)
Entry created
2012-04-04
Entry updated
2025-04-10

Source Cellosaurus

Problems1

ProblemCellosaurus's note
ContaminatedShown to be a U-937 derivative (PubMed=12592342; PubMed=20143388). Originally thought to originate from the peripheral blood of a 57 year old male patient with monocytic leukemia (M5b).

Papers4

PaperJournalYearHow we knowRetractedSource
Check your cultures! A list of cross-contaminated or misidentified cell lines.Int J Cancer2010Cellosaurus cites itPubMed
False leukemia-lymphoma cell lines: an update on over 500 cell lines.Leukemia2003Cellosaurus cites itPubMed
Tandem duplication of the FLT3 gene is found in acute lymphoblastic leukaemia as well as acute myeloid leukaemia but not in myelodysplastic syndrome or juvenile chronic myelogenous leukaemia in children.
Br J Haematol1999Cellosaurus cites itPubMed
Establishment of a novel human macrophage-like cell line, MABS-1, derived from a human monocytic leukemia cell line, MOBS-1.1997Cellosaurus cites itDOI

Relatives2

RelationCell lineAccessionProblemSource
ParentU-937CVCL_0007Has a recorded problemCell lines
Derived from itMABS-1CVCL_RX32Has a recorded problemCell lines

Cell banks0

None in this release.

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_8442

GET https://conductscience.org/api/cell-lines/v1/CVCL_8442/problems