Cell line · CVCL_J431
RPMI-8226/Dox40
Cancer cell line, Homo sapiens. Plasma cell myeloma. 6 papers.
4 sourcescell-lines-2026-11-14-0.1.0
Cite this record
ConductScience Library. RPMI-8226/Dox40. Cell lines, record CVCL_J431. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_J431
On this page
Cell line
As Cellosaurus gives it.
- Name
- RPMI-8226/Dox40
- Accession
- CVCL_J431
- RRID
- RRID:CVCL_J431
- Synonyms
- RPMI 8226/DOX40, RPMI-8226DOX40, 8226/DOX40, 8226/Dox40, 8226/Dox(40), 8226 Dox40, 8226Dox40, Dox40
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 61Y
- Category
- Cancer cell line
- Diseases
- Plasma cell myeloma (NCIt C3242); Multiple myeloma (ORDO Orphanet_29073)
- Derived from
- Peripheral blood (in situ)
- Cell type
- Plasma cell
- Parent
- RPMI-8226 (CVCL_0014)
- Entry created
- 2013-02-11
- Entry updated
- 2025-08-14
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers6
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| Anti-myeloma activity of the CXCR4 antagonist WZ811. | J Mol Med (Berl) | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. | Cancer Res | 2001 | Cellosaurus cites it | PubMed | |
| Breast cancer resistance protein is localized at the plasma membrane in mitoxantrone- and topotecan-resistant cell lines. | Cancer Res | 2000 | Cellosaurus cites it | PubMed | |
| TRAG-3, a novel gene, isolated from a taxol-resistant ovarian carcinoma cell line. | Gene | 1999 | Cellosaurus cites it | PubMed | |
| Elimination of chemoresistant multiple myeloma clonogenic colony-forming cells by combined treatment with a plasma cell-reactive monoclonal antibody and a P-glycoprotein-reactive monoclonal antibody. | Cancer Res | 1989 | Cellosaurus cites it | PubMed | |
| Immunohistochemical detection and quantitation of P-glycoprotein in multiple drug-resistant human myeloma cells: association with level of drug resistance and drug accumulation. | Blood | 1989 | Cellosaurus cites it | PubMed |
Relatives2
| Relation | Cell line | Accession | Problem | Source |
|---|---|---|---|---|
| Parent | RPMI-8226 | CVCL_0014 | Cell lines | |
| Derived from it | RPMI-8226/MDR10V | CVCL_J433 | Cell lines |
Cell banks0
None in this release.
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_J431
GET https://conductscience.org/api/cell-lines/v1/CVCL_J431/problems