Comparison · NCT00326612-a30e65e2
Intranasal Midazolam vs Rectal Diazepam: Respiratory Depression Requiring Oxygen at Discharge From the Emergency Department.
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Intranasal Midazolam vs Rectal Diazepam: Respiratory Depression Requiring Oxygen at Discharge From the Emergency Department. Trial comparisons, record NCT00326612-a30e65e2. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00326612-a30e65e2
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.06 | 0.0206 | 0.162 | wilson | |
| Risk in group 2 | 0.0238 | 0.00422 | 0.123 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0362 | -0.0707 | 0.14 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 2.52 | 0.272 | 23.3 | log | |
| Odds ratio, group 1 over group 2 | 2.62 | 0.262 | 26.1 | log | |
| Number needed to treat, for one more participant with the outcome on Intranasal Midazolam than on Rectal Diazepam | 27.6 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Intranasal Midazolam | Patients who required oxygen at discharge from the Emergency Department | 3 | 50 | OG000 |
| Group 2 | Rectal Diazepam | Includes intubation | 1 | 42 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Respiratory Depression Requiring Oxygen at Discharge From the Emergency Department.
- Description
- Respiratory depression was defined as requiring oxygen at discharge from the Emergency Department.
- Time frame
- 24 hours
- Population
- Analysis was per protocol
Source ClinicalTrials.gov
Trial
- Title
- Intranasal Midazolam Versus Rectal Diazepam for Treatment of Seizures
- NCT number
- NCT00326612
- Phases
- PHASE2
- Conditions
- Seizures
- Interventions
- Midazolam, Diazepam
- Lead sponsor
- University of Utah
- Results first posted
- 2011-10-26
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00326612?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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