Comparison · NCT00326612-a90138d2
Intranasal Midazolam vs Rectal Diazepam: Number of Patients That Were Admitted to the Hospital After Their Seizure and Use of Study Medication.
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Intranasal Midazolam vs Rectal Diazepam: Number of Patients That Were Admitted to the Hospital After Their Seizure and Use of Study Medication. Trial comparisons, record NCT00326612-a90138d2. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00326612-a90138d2
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.08 | 0.0315 | 0.188 | wilson | |
| Risk in group 2 | 0.0714 | 0.0246 | 0.19 | wilson | |
| Risk difference, group 1 minus group 2 | 0.00857 | -0.12 | 0.127 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.12 | 0.265 | 4.73 | log | |
| Odds ratio, group 1 over group 2 | 1.13 | 0.238 | 5.36 | log | |
| Number needed to treat, for one more participant with the outcome on Intranasal Midazolam than on Rectal Diazepam | 117 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Intranasal Midazolam | 0.2 mg/kg Intranasal Midazolam for a seizure longer than 5 minutes | 4 | 50 | OG000 |
| Group 2 | Rectal Diazepam | 0.3-0.5 Rectal Diazepam for a seizure lasting longer than 5 minutes | 3 | 42 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Patients That Were Admitted to the Hospital After Their Seizure and Use of Study Medication.
- Description
- Time frame
- 24 hours
- Population
Source ClinicalTrials.gov
Trial
- Title
- Intranasal Midazolam Versus Rectal Diazepam for Treatment of Seizures
- NCT number
- NCT00326612
- Phases
- PHASE2
- Conditions
- Seizures
- Interventions
- Midazolam, Diazepam
- Lead sponsor
- University of Utah
- Results first posted
- 2011-10-26
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00326612?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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