Comparison · NCT00367341-e22a79ef
Escitalopram vs Cognitive Behavioral Therapy: Response Defined as 50% Change in Hamilton Depression Rating Scale-17 Score at 12 Weeks
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Escitalopram vs Cognitive Behavioral Therapy: Response Defined as 50% Change in Hamilton Depression Rating Scale-17 Score at 12 Weeks. Trial comparisons, record NCT00367341-e22a79ef. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00367341-e22a79ef
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.563 | 0.393 | 0.718 | wilson | |
| Risk in group 2 | 0.581 | 0.408 | 0.736 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0181 | -0.248 | 0.215 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.969 | 0.632 | 1.49 | log | |
| Odds ratio, group 1 over group 2 | 0.929 | 0.342 | 2.52 | log | |
| Number needed to treat, for one fewer participant with the outcome on Escitalopram than on Cognitive Behavioral Therapy | 55.1 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Escitalopram | escitalopram : Participants will receive treatment with escitalopram for 12 weeks. | 18 | 32 | OG000 |
| Group 2 | Cognitive Behavioral Therapy | Cognitive Behavioral Therapy (CBT) : CBT will include 16 1 hour sessions provided over 12 weeks. | 18 | 31 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Response Defined as 50% Change in Hamilton Depression Rating Scale-17 Score at 12 Weeks
- Description
- Number of participants with a 50% change from Baseline on the Hamilton Depression Rating Scale-17-item score
- Time frame
- Measured at week 12.
- Population
- completers
Source ClinicalTrials.gov
Trial
- Title
- Imaging Predictors of Treatment Response in Depression
- NCT number
- NCT00367341
- Phases
- NA
- Conditions
- Major Depressive Disorder
- Interventions
- escitalopram, Cognitive Behavioral Therapy (CBT)
- Lead sponsor
- Emory University
- Results first posted
- 2014-01-09
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00367341?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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