Trial · NCT00367341

Imaging Predictors of Treatment Response in Depression

NCT00367341, Not applicable, Completed, Emory University; results first posted 2014-01-09

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. Imaging Predictors of Treatment Response in Depression. Trials, record NCT00367341. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00367341

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: Imaging Predictors of Treatment Response in Depression
NCT number: NCT00367341
Status: Completed
Phases: Not applicable
Enrollment: 82 participants, actual
Lead sponsor: Emory University
Conditions: Major Depressive Disorder
Interventions: escitalopram, Cognitive Behavioral Therapy (CBT)
First posted: 2006-08-22
Last updated: 2014-01-09
Results first posted: 2014-01-09

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	Remission Defined as Hamilton Depression Rating Scale-17 Score of Less Than or Equal to 7 at 12 Weeks	Measured at week 12	\# of study participants with Hamilton Depression-17-item score less than or equal to 7.
Secondary	Response Defined as 50% Change in Hamilton Depression Rating Scale-17 Score at 12 Weeks	Measured at week 12.	Number of participants with a 50% change from Baseline on the Hamilton Depression Rating Scale-17-item score

Source ClinicalTrials.gov

Outcomes2

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	Remission Defined as Hamilton Depression Rating Scale-17 Score of Less Than or Equal to 7 at 12 Weeks	Measured at week 12	completed study participants in 12-week-trial	participants	NUMBER
SECONDARY	Response Defined as 50% Change in Hamilton Depression Rating Scale-17 Score at 12 Weeks	Measured at week 12.	completers	participants	NUMBER

Source ClinicalTrials.gov

Results by group4

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Value	Units
Remission Defined as Hamilton Depression Rating Scale-17 Score of Less Than or Equal to 7 at 12 Weeks	Escitalopram	12	participants
Remission Defined as Hamilton Depression Rating Scale-17 Score of Less Than or Equal to 7 at 12 Weeks	Cognitive Behavioral Therapy	12	participants
Response Defined as 50% Change in Hamilton Depression Rating Scale-17 Score at 12 Weeks	Escitalopram	18	participants
Response Defined as 50% Change in Hamilton Depression Rating Scale-17 Score at 12 Weeks	Cognitive Behavioral Therapy	18	participants

Source ClinicalTrials.gov

Participant flow6

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Overall Study	STARTED	Escitalopram	42
Overall Study	STARTED	Cognitive Behavioral Therapy	40
Overall Study	COMPLETED	Escitalopram	40
Overall Study	COMPLETED	Cognitive Behavioral Therapy	40
Overall Study	NOT COMPLETED	Escitalopram	2
Overall Study	NOT COMPLETED	Cognitive Behavioral Therapy	0

Source ClinicalTrials.gov

Adverse events30

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

Type	Event	Organ system	Group	Affected	At risk	Events
other	diarrhea	Gastrointestinal disorders	Escitalopram	5	42	5
other	diarrhea	Gastrointestinal disorders	Cognitive Behavioral Therapy	2	40	2
other	fatigue	General disorders	Escitalopram	5	42	5
other	fatigue	General disorders	Cognitive Behavioral Therapy	2	40	2
other	flu	Infections and infestations	Escitalopram	3	42	3
other	flu	Infections and infestations	Cognitive Behavioral Therapy	0	40	0
other	dizziness	General disorders	Escitalopram	5	42	5
other	dizziness	General disorders	Cognitive Behavioral Therapy	0	40	0
other	dry mouth	General disorders	Escitalopram	3	42	3
other	dry mouth	General disorders	Cognitive Behavioral Therapy	0	40	0

1 to 10 of 30Source ClinicalTrials.gov

See all 30 adverse events

Adverse event totals6

The totals the trial posted for each group.

Total	Group	Affected	At risk
Total, all-cause mortality	Escitalopram
Total, all-cause mortality	Cognitive Behavioral Therapy
Total, other adverse events	Escitalopram	33	42
Total, other adverse events	Cognitive Behavioral Therapy	21	40
Total, serious adverse events	Escitalopram	0	42
Total, serious adverse events	Cognitive Behavioral Therapy	0	40

Source ClinicalTrials.gov

Papers2

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as	Source
23760393	RESULT	PubMed
24462230	DERIVED	PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons3

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

Comparison	Source
Escitalopram vs Cognitive Behavioral Therapy: Remission Defined as Hamilton Depression Rating Scale-17 Score of Less Than or Equal to 7 at 12 Weeks	Trial comparisons
Escitalopram vs Cognitive Behavioral Therapy: Response Defined as 50% Change in Hamilton Depression Rating Scale-17 Score at 12 Weeks	Trial comparisons
Escitalopram vs Cognitive Behavioral Therapy: serious adverse events	Trial comparisons

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT00367341

GET https://conductscience.org/api/trials/v1/NCT00367341/events?page=2

API reference For AI assistants