Comparison · NCT00390546-183d8766
Digoxin vs Propranolol: Number of Treated Patients Experiencing First SVT Recurrence
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Digoxin vs Propranolol: Number of Treated Patients Experiencing First SVT Recurrence. Trial comparisons, record NCT00390546-183d8766. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00390546-183d8766
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.188 | 0.0889 | 0.353 | wilson | |
| Risk in group 2 | 0.308 | 0.186 | 0.464 | wilson | |
| Risk difference, group 1 minus group 2 | -0.12 | -0.305 | 0.0855 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.609 | 0.258 | 1.44 | log | |
| Odds ratio, group 1 over group 2 | 0.519 | 0.17 | 1.59 | log | |
| Number needed to treat, for one fewer participant with the outcome on Digoxin than on Propranolol | 8.32 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Digoxin | The first 2 doses of digoxin were administered orally at 0.010 mg/kg per dose TID, then 0.0035 mg/kg per dose TID for the third and subsequent doses. | 6 | 32 | OG000 |
| Group 2 | Propranolol | Single dose administered orally at 0.5/kg per dose and increased to 1.0 mg/kg per dose TID for the second and subsequent doses. | 12 | 39 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Treated Patients Experiencing First SVT Recurrence
- Description
- Infants treated with propranolol or digoxin
- Time frame
- up to 110 days of treatment
- Population
Source ClinicalTrials.gov
Trial
- Title
- Multicenter Study of Antiarrhythmic Medications for Treatment of Infants With Supraventricular Tachycardia
- NCT number
- NCT00390546
- Phases
- PHASE3
- Conditions
- Supraventricular Tachycardia
- Interventions
- Digoxin, Propranolol
- Lead sponsor
- University of British Columbia
- Results first posted
- 2013-08-22
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00390546?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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