Comparison · NCT00467363-944bb19c
Aspirin vs Placebo: Abruption
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Aspirin vs Placebo: Abruption. Trial comparisons, record NCT00467363-944bb19c. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00467363-944bb19c
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0114 | 0.00552 | 0.0233 | wilson | |
| Risk in group 2 | 0.00816 | 0.00349 | 0.019 | wilson | |
| Risk difference, group 1 minus group 2 | 0.00323 | -0.00906 | 0.016 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.4 | 0.445 | 4.37 | log | |
| Odds ratio, group 1 over group 2 | 1.4 | 0.442 | 4.44 | log | |
| Number needed to treat, for one more participant with the outcome on Aspirin than on Placebo | 310 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Aspirin | 81mg of low-dose aspirin plus 400micrograms of folic acid.~acetylsalicylic-acid (aspirin): 81mg of low-dose aspirin plus 400micrograms of folic acid. | 7 | 615 | OG000 |
| Group 2 | Placebo | 400micrograms of folic acid.~Folic acid: 400micrograms of folic acid. | 5 | 613 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Abruption
- Description
- Partial or complete abruption (ie, premature separation of the placenta)
- Time frame
- until delivery
- Population
Source ClinicalTrials.gov
Trial
- Title
- The Effects of Aspirin in Gestation and Reproduction
- NCT number
- NCT00467363
- Phases
- NA
- Conditions
- Birth, Spontaneous Abortion
- Interventions
- acetylsalicylic-acid (aspirin), Folic acid
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Results first posted
- 2014-05-14
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00467363?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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