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Comparison · NCT00901628-808eebbb

Periarticular Injection Group vs No Injection Group: Participant Number of Postoperative Nausea and Vomiting During 24 Hours After Surgery

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Periarticular Injection Group vs No Injection Group: Participant Number of Postoperative Nausea and Vomiting During 24 Hours After Surgery. Trial comparisons, record NCT00901628-808eebbb. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00901628-808eebbb

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.4490.3190.587wilson
Risk in group 20.2880.1830.423wilson
Risk difference, group 1 minus group 20.161-0.02670.334newcombe hybrid score
Risk ratio, group 1 over group 21.560.9182.64log
Odds ratio, group 1 over group 22.010.8834.58log
Number needed to treat, for one more participant with the outcome on Periarticular Injection Group than on No Injection Group6.23from the risk difference intervalthe interval includes no difference

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Periarticular Injection GroupPeriarticular injection with ropivacaine, morphine, ketorolac, epinephrine, cefuroxime2249OG000
Group 2No Injection Groupusual postoperative care without periarticular injection1552OG001

Outcome

Type
SECONDARY
Title
Participant Number of Postoperative Nausea and Vomiting During 24 Hours After Surgery
Description
An independent investigator assessed participant number of postoperative nausea and vomiting during 24 hours after surgery. Nausea was defined as a subjective unpleasant sensation associated with awareness of the urge to vomit; and vomiting, as the forceful expulsion of gastric contents from the mouth.
Time frame
24 hours after surgery
Population

Source ClinicalTrials.gov

Trial

Title
Periarticular Multimodal Drug Injections in Total Knee Arthroplasty
NCT number
NCT00901628
Phases
PHASE4
Conditions
Osteoarthritis, Knee
Interventions
ropivacaine, morphine sulfate, ketorolac, epinephrine, cefuroxime
Lead sponsor
Seoul National University Hospital
Results first posted
2013-01-25

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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