Comparison · NCT01435018-2c4a05bb
BV+ART vs PTX+ART: Number of Participants With Objective Response for BV+ART vs. PTX+ART
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. BV+ART vs PTX+ART: Number of Participants With Objective Response for BV+ART vs. PTX+ART. Trial comparisons, record NCT01435018-2c4a05bb. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01435018-2c4a05bb
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.606 | 0.521 | 0.685 | wilson | |
| Risk in group 2 | 0.659 | 0.577 | 0.733 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0534 | -0.166 | 0.061 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.919 | 0.766 | 1.1 | log | |
| Odds ratio, group 1 over group 2 | 0.795 | 0.484 | 1.3 | log | |
| Number needed to treat, for one fewer participant with the outcome on BV+ART than on PTX+ART | 18.7 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | BV+ART | Bleomycin and Vincristine plus ART (co-formulated Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate) | 80 | 132 | OG000 |
| Group 2 | PTX+ART | Paclitaxel plus ART (co-formulated Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate) | 91 | 138 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants With Objective Response for BV+ART vs. PTX+ART
- Description
The number of participants with objective response (complete response or partial response) as best overall KS response in Step 1. Overall KS response status (complete response, partial response, stable, disease progression) was based on comparing follow-up KS response to study entry or best KS response with respect to clinical assessment of KS cutaneous lesions (count, character and marker lesion area), oral KS, visceral KS and tumor-associated edema and as described in the publications (Krown et al 1989, Cianfrocca et al 2002).
- Time frame
- From study entry up to week 144
- Population
- All eligible participants who initiated study chemotherapy with available data as of March 2018.
Source ClinicalTrials.gov
Trial
- Title
- Three Chemo Regimens as an Adjunct to ART for Treatment of Advanced AIDS-KS
- NCT number
- NCT01435018
- Phases
- PHASE3
- Conditions
- HIV-1 Infection
- Interventions
- Etoposide (ET), Bleomycin and Vincristine (BV), Paclitaxel (PTX), Co-formulated Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate (EFV/FTC/TDF)
- Lead sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
- Results first posted
- 2019-04-08
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01435018?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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